51600-24-9 Usage
General Description
(S)-(-)-1-(1-Naphthyl)ethylamine hydrochloride, also known as (S)-(-)-α-methyl-1-naphthalenemethylamine, is a chemical compound with the formula C12H13N. It is a chiral amine that is commonly used in organic synthesis as a building block for various pharmaceuticals and agrochemicals. (S)-(-)-1-(1-NAPHTHYL)ETHYLAMINE HYDROC& is a white to off-white crystalline powder that is soluble in water and ethanol. It is also known for its potential as a ligand in asymmetric catalysis, making it a valuable tool in chemical research and development. Additionally, it is used as a reagent in the synthesis of various biologically active compounds and as a precursor in the production of a wide range of chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 51600-24-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,6,0 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51600-24:
(7*5)+(6*1)+(5*6)+(4*0)+(3*0)+(2*2)+(1*4)=79
79 % 10 = 9
So 51600-24-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N.ClH/c1-9(13)11-8-4-6-10-5-2-3-7-12(10)11;/h2-9H,13H2,1H3;1H/t9-;/m0./s1
51600-24-9Relevant articles and documents
Rhodium-catalyzed asymmetric hydrogenation of unprotected NH imines assisted by a thiourea
Zhao, Qingyang,Wen, Jialin,Tan, Renchang,Huang, Kexuan,Metola, Pedro,Wang, Rui,Anslyn, Eric V.,Zhang, Xumu
supporting information, p. 8467 - 8470 (2014/08/18)
Asymmetric hydrogenation of unprotected NH imines catalyzed by rhodium/bis(phosphine)-thiourea provided chiral amines with up to 97% yield and 95% ee. 1HNMR studies, coupled with control experiments, implied that catalytic chloride-bound intermediates were involved in the mechanism through a dual hydrogen-bonding interaction. Deuteration experiments proved that the hydrogenation proceeded through a pathway consistent with an imine.
