5164-76-1Relevant articles and documents
Selective esterification of nonconjugated carboxylic acids in the presence of conjugated or aromatic carboxylic acids under mild conditions
Anand, Ramesh C.,Vimal,Milhotra, Archana
, p. 378 - 379 (1999)
Nonconjugated carboxylic acids are selectively esterified in good yields in the presence of conjugated or aromatic carboxylic acids by stirring over Amberlyst-15 in alcohol at room temperature.
Rhodium-catalysed alkoxylation/acetalization of diazo compounds: One-step synthesis of highly functionalised quaternary carbon centres
Pospech, Jola,Lennox, Alastair J. J.,Beller, Matthias
supporting information, p. 14505 - 14508 (2015/09/28)
An intermolecular tandem reaction for the rapid build-up of densely functionalised α-alkoxy-β-oxo-esters has been developed. This novel process applies the easy to handle trimethyl orthoformate as a C1-building block in the rhodium(ii)-catalysed alkoxylation/acetalization of donor-acceptor substituted diazo compounds. The concomitant C-O/C-C bond formation reaction gives products with unique quaternary carbon centers, substituted by groups of different oxidation level (ester, protected aldehyde and alkoxide).
Influence of functional substitution of allyl halides on their ni(co)4 promoted carbonylative cycloaddition with acetylenes
Camps, Francisco,Moreto, Josep M.,Pages, Lluis
, p. 3147 - 3162 (2007/10/02)
The effect of functional substitution of allyl halides on the outcome of the title reaction has been studied. Electron withdrawing and olefinic groups had different effects depending on their location. When they were placed at the central position of the allyl moiety carbonylative cycloaddition was found to be the main reaction, in acetone, to yield exclusively cyclohexenone (or aromatic) derivatives. In contrast, the same groups at the terminal site and in exteded conjugation with the allylic funtion were shown to favour competing side reactions such as allyl self-coupling. However, only cyclopentenones were obtained from either centrally or terminally substituted silylallyl halides. Substitution at both ends of the allyl moiety led to the formation of 4,5-disubstituted cyclopentenones. Important mechanistic information could be achieved from determination of the relative stereochemistry in these compounds.