516526-98-0

Basic information

• Product Name: 2-bromo-1,3-bis(1-cyano-1-methylethyl)benzene
• Synonyms: 2-bromo-1,3-bis(1-cyano-1-methylethyl)benzene
• CAS NO: 516526-98-0
• Molecular Weight: 291.19
• Mol File: 516526-98-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-bromo-1,3-bis(1-cyano-1-methylethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1,3-bis(1-cyano-1-methylethyl)benzene(516526-98-0)
• EPA Substance Registry System: 2-bromo-1,3-bis(1-cyano-1-methylethyl)benzene(516526-98-0)

Safety Data

• Hazardous Substances Data: 516526-98-0(Hazardous Substances Data)

Upstream product

• 74-88-4 methyl iodide 

Downstream Products

• 1403386-94-6 2-(4-bromo-3,5-di-tert-butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1403387-18-7 methyl 2,6-di-tert-butyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 1403387-19-8 methyl 2,6-di-tert-butylbenzoate 
• 253584-86-0 2,6-di-tert-butylbenzoic acid 
• 127043-84-9 2,6-di-t-butylphenylphosphonous dichloride 
• 19715-32-3 2-bromo-1,3-di-tert-butylbenzene 
• 516526-99-1 2-bromo-1,3-bis(1-formyl-1-methylethyl)benzene 

Relevant articles and documents

PYRROLO SULFONAMIDE COMPOUNDS FOR MODULATION OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORGAMMA, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES

The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administrating these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo sulfonamide compounds of Formula (1) and the enantiomers, diastereomers, tautomers, solvates and pharmaceutically acceptable salts thereof.

Development of a new sterically protecting auxiliary of the metacyclophane type and application to unsymmetrical diphosphenes, 1,3-diphosphaallene and 1,4-diphosphabutatriene

A new bulky bromobenzene of the metacyclophane type was converted to an unsymmetrically substituted 1,4-diphos-phabutatriene whose spin-spin coupling constant (3JPP) turned out to be larger, for the first time, than the 2J