51664-50-7

Basic information

• Product Name: Silane, bis(2-bromoethyl)dimethyl-
• Synonyms: Silane,bis(2-bromoethyl)dimethyl
• CAS NO: 51664-50-7
• Molecular Formula: C6H14Br2Si
• Molecular Weight: 274.071
• Mol File: 51664-50-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 115-116 °C(Press: 9 Torr)
• Density: 1.444±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Silane, bis(2-bromoethyl)dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, bis(2-bromoethyl)dimethyl-(51664-50-7)
• EPA Substance Registry System: Silane, bis(2-bromoethyl)dimethyl-(51664-50-7)

Safety Data

• Hazardous Substances Data: 51664-50-7(Hazardous Substances Data)

Upstream product

• 10519-87-6 divinyldimethylsilane 

Downstream Products

• 802982-62-3 1-(4-methoxybenzyl)-4,4-dimethyl-4-silapiperidine 
• 130596-61-1 1-benzyl-4,4-dimethyl-[1,4]azasilinane hydrochloride 
• 130596-62-2 4,4-dimethyl-4-silapiperidine hydrochloride 
• 1430321-69-9 (R)-5-(azidomethyl)-3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3,5-difluorophenyl)oxazolidin-2-one 
• 1430321-51-9 (R)-5-(azidomethyl)-3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3-fluorophenyl)oxazolidin-2-one 
• 1430321-68-8 (R)-(3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3,5-difluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate 
• 1430321-64-4 (S)-tert-butyl ((3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3,5-difluorophenyl)-2-oxooxazolidin-5-yl)methyl)carbamate 
• 1430321-59-7 (R)-5-((1H-l,2,3-triazol-1-yl)methyl)-3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3,5-difluorophenyl)oxazolidin-2-one 
• 1430321-52-0 (R)-5-((1H-1,2,3-triazol-1-yl)methyl)-3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3-fluorophenyl)oxazolidin-2-one 
• 1430321-58-6 (R)-3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3,5-difluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one 
• 1430321-49-5 (R)-3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one 
• 1430321-57-5 (S)-O-methyl (3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3,5-difluorophenyl)-2-oxooxazolidin-5-yl)methylcarbamothioate 
• 1430321-48-4 (S)-O-methyl ((3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)carbamothioate 
• 1430321-56-4 (S)-methyl (3-(4-(4,4-dimethyl-1,4-azasilinan-1-yl)-3,5-difluorophenyl)-2-oxooxazolidin-5-yl)methylcarbamate 

Relevant articles and documents

[...] piperidine derivative and its preparation method and use thereof (by machine translation)

The present invention provides a novel structure sila piperidine derivative or a pharmaceutically acceptable salt or solvate thereof, wherein the structure general formula is represented by a formula (I). The present invention further provides a drug composition containing a pharmaceutically effective amount of the sila piperidine derivative or the pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable excipient or additive. The present invention further discloses a synthesis method for the sila piperidine derivative, wherein dichloro-substituted silane is adopted as a starting raw material, and multi-step reactions are integrated and performed in one pot to obtain the high purity pharmaceutical intermediate for preparing the camptothecin sila derivative, wherein the synthesis route is short, the reaction environments, especially the temperature, the pressure and the like, are safe and controlled, and the characteristic of green environmental protection is provided. In addition, the preparation raw materials have the wide sources and are easy to obtain, the preparation method is simple and is easy to operate, the reaction conditions are mild, the synthesized product yield is high, and great industrial application values are provided.

SILA ANALOGS OF OXAZOLIDINONE DERIVATIVES AND SYNTHESIS THEREOF

The invention discloses silaanalogs of oxazolidinone compounds, to pharmaceutical compositions and to the synthesis of the oxazolidinone derivatives of formula I. The invention further relates to methods of treating a subject suffering with gram positive pathogens including those resistant to methicillin and vancomycin using the compound(s) or modulation of coagulation properties of blood-clotting cascade or compositions of the oxazolidinone derivatives of the invention.

NOVEL TRIAZOLOPYRIMIDINE DERIVATIVES

The present invention relates to novel triazolopyrimidine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein the substituents are as defined in claim 1.