51686-78-3

Basic information

• Product Name: 2,4-Dibromonitrobenzene
• Synonyms: 2,4-Dibromonitrobenzene;2,4-Dibromo-1-nitrobenzene;,3-Dibromo-4-nitrobenzene;1,3-Dibromo-4-nitrobenzene;Benzene, 2,4-dibroMo-1-nitro-
• CAS NO: 51686-78-3
• Molecular Formula: C₆H₃Br₂NO₂
• Molecular Weight: 280.90152
• Mol File: 51686-78-3.mol
• Article Data: 19

Chemical Properties

• Melting Point: 61-62℃
• Boiling Point: 270℃
• Flash Point: 117℃
• Appearance: Yellow/Crystalline Powder
• Density: 2.101
• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: 1.6400 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 2,4-Dibromonitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dibromonitrobenzene(51686-78-3)
• EPA Substance Registry System: 2,4-Dibromonitrobenzene(51686-78-3)

Safety Data

• HazardClass: 6.1
• Hazardous Substances Data: 51686-78-3(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow powder

InChI:InChI=1/C6H3Br2NO2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H

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Relevant articles and documents

Imidazolyl benzimidazoles and imidazo[4,5-b]pyridines as potent p38α MAP kinase inhibitors with excellent in vivo antiinflammatory properties

Herein we report investigations into the p38α MAP kinase activity of trisubstituted imidazoles that led to the identification of compounds possessing highly potent in vivo activity. The SAR of a novel series of imidazopyridines is demonstrated as well, resulting in compounds possessing cellular potency and enhanced in vivo activity in the rat collagen-induced arthritis model of chronic inflammation.

Synthesis and: In vitro evaluation of naphthalimide-benzimidazole conjugates as potential antitumor agents

A series of novel naphthalimide-benzimidazoles was designed and synthesized for the first time and studied for their effect on antiproliferative activity. Some of these compounds possessed good antitumor activity towards the tested cancer cell lines. Noticeably, (diethylamino)ethyl 15 and (dimethylamino)ethyl 23 derivatives displayed superior antiproliferative activity towards human cancer cell lines with MG-MID GI50 values of 1.43 and 1.83 μM, respectively. Preliminary investigation revealed that compounds 15 and 23 might bind with ct-DNA through the intercalation mode which is responsible for potent bioactivity. Moreover, transportation behaviour indicated that these molecules could efficiently bind to and be carried by bovine albumin, and the hydrogen bonding and hydrophobic interactions played important roles in interaction with serum albumin.

ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME

The present invention provides an organic compound for an organic light emitting diode. An example of the organic compound is represented by: