51719-67-6

Basic information

• Product Name: 2-(3,4,5-triMethylphenyl)acetic acid
• Synonyms: 2-(3,4,5-triMethylphenyl)acetic acid;3,4,5-Trimethylbenzeneacetic acid;3,4,5-Trimethylphenylacetic acid
• CAS NO: 51719-67-6
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.22766
• Mol File: 51719-67-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 317°Cat760mmHg
• Flash Point: 214.1°C
• Appearance: /
• Density: 1.075
• Vapor Pressure: 0.000166mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: 2-(3,4,5-triMethylphenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4,5-triMethylphenyl)acetic acid(51719-67-6)
• EPA Substance Registry System: 2-(3,4,5-triMethylphenyl)acetic acid(51719-67-6)

Safety Data

• Hazardous Substances Data: 51719-67-6(Hazardous Substances Data)

Usage

Structure

A phenyl group with three methyl groups attached and an acetic acid group (-COOH)

Derivative

Acetic acid

Usage

Organic synthesis, pharmaceutical research (building block for various pharmaceuticals and agrochemicals), fragrance ingredient in perfumes and cosmetics

Potential applications

Production of polymers and plastics

Safety precautions

Potential for causing skin and eye irritation; should be handled and stored in a controlled environment.

InChI:InChI=1/C11H14O2/c1-7-4-10(6-11(12)13)5-8(2)9(7)3/h4-5H,6H2,1-3H3,(H,12,13)

Upstream product

• 2047-21-4 3,4,5-trimethylacetophenone 
• 58474-29-6 4-[(3,4,5-trimethyl-phenyl)-thioacetyl]-morpholine 

Downstream Products

• 660415-26-9 E-2-(3',4',5'-trimethylphenyl)-3-(3''-fluoro-4''-methoxyphenyl)prop-2-enoic acid 
• 671232-88-5 7-chloro-4-hydroxy-6-iodo-3-(3,4,5-trimethylphenyl)-1H-quinolin-2-one 
• 671232-87-4 methyl 4-chloro-5-iodo-2-N-(3,4,5-trimethylphenyl)acetylaminobenzoate 
• 335293-20-4 4-(2-(N-tert-butoxycarbonylazetidin-2(S)-yl)ethoxy)-7-chloro-2-oxo-3-(3,4,5-trimethylphenyl)-1,2-dihydroquinoline-6-carboxylic acid pyrimidin-4-ylamide 
• 335293-24-8 4-(2-(N-tert-butoxycarbonylazetidin-2(S)-yl)ethoxy)-7-chloro-2-oxo-3-(3,4,5-trimethylphenyl)-1,2-dihydoquinoline-6-carboxylic acid 
• 362604-16-8 dimethyl 6-N-(3,4,5-trimethylphenyl)acetylamino-4-chloro-1,3-isophthalate 
• 335293-17-9 6-carbomethoxy-7-chloro-4-hydroxy-3-(3,4,5-trimethylphenyl)-1H-quinolin-2-one 
• 660415-28-1 E-2-(3',4',5'-trimethylphenyl)-3-(3''-(2''',3''',5''',6'''-tetrafluoro-4'''-trifluoromethylphenyloxy)-4''-methoxyphenyl)-prop-2-enoic acid 
• 335293-23-7 3,4,5-trimethylphenylacetyl chloride 

Relevant articles and documents

Quinolones as gonadotropin releasing hormone (GnRH) antagonists: Simultaneous optimization of the C(3)-aryl and C(6)-substituents

A series of 3-arylquinolones was prepared and evaluated for their ability to act as gonadotropin releasing hormone (GnRH) antagonists. A variety of substitution patterns of the 3-aryl substituent are described. The 3,4,5-trimethylphenyl substituent (23h) was found to be optimal. (C) 2000 Elsevier Science Ltd. All rights reserved.