51768-56-0

Basic information

• Product Name: Benzene, 1-ethyl-3,5-dimethoxy-
• CAS NO: 51768-56-0
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 51768-56-0.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzene, 1-ethyl-3,5-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-ethyl-3,5-dimethoxy-(51768-56-0)
• EPA Substance Registry System: Benzene, 1-ethyl-3,5-dimethoxy-(51768-56-0)

Safety Data

• Hazardous Substances Data: 51768-56-0(Hazardous Substances Data)

Upstream product

• 39151-19-4 1-(3,5-dimethoxyphenyl)ethan-1-one 
• 67-56-1 methanol 
• 54531-77-0 4,4-<1,2-ethanediylbis(thio)>cyclohexyl benzoate 
• 75-89-8 2,2,2-trifluoroethanol 
• 14950-55-1 rac-1-(3,5-dimethoxyphenyl)ethan-1-ol 
• 108-94-1 cyclohexanone 
• 54531-74-7 4,4-<1,2-ethanediylbis(thio)>cyclohexanone 
• 38513-65-4 3,5-dimethoxybenzyl acetate 
• 108864-34-2 1-ethyl-3,5-dimethoxycyclohexa-2,5-diene-1-carboxylic acid 
• 40243-87-6 3,5-dimethoxystyrene 
• 78398-36-4 (R)-(+)-1-(3,5-dimethoxyphenyl)ethanol 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 705-76-0 3,5-dimethoxybenzyl alcohol 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 1197155-72-8 1,5-dimethoxy-3-ethylcyclohexa-1,4-diene 
• 709014-52-8 2-ethyl-4-benzyloxy-6-methoxy-benzaldehyde 
• 709027-59-8 2-ethyl-4-benzyloxy-6-hydroxy-benzaldehyde 
• 709014-16-4 2-ethyl-6-hydroxy-4-methoxy-benzaldehyde 
• 709024-56-6 2-ethyl-4-hydroxy-6-methoxy-benzaldehyde 
• 63521-10-8 2-ethyl-4,6-dihydroxy-3-methyl-benzaldehyde 
• 39503-15-6 2-ethyl-4,6-dihydroxy-benzaldehyde 
• 81633-93-4 5-ethyl-4-methyl-resorcinol 
• 39503-16-7 2-ethyl-4,6-dimethoxy-benzaldehyde 
• 88640-66-8 3-ethyl-5-methoxy-phenol 

Relevant articles and documents

Design of Negative and Positive Allosteric Modulators of the Cannabinoid CB2Receptor Derived from the Natural Product Cannabidiol

Cannabidiol (CBD), the second most abundant of the active compounds found in the Cannabis sativa plant, is of increasing interest because it is approved for human use and is neither euphorizing nor addictive. Here, we design and synthesize novel compounds taking into account that CBD is both a partial agonist, when it binds to the orthosteric site, and a negative allosteric modulator, when it binds to the allosteric site of the cannabinoid CB2 receptor. Molecular dynamic simulations and site-directed mutagenesis studies have identified the allosteric site near the receptor entrance. This knowledge has permitted to perform structure-guided design of negative and positive allosteric modulators of the CB2 receptor with potential therapeutic utility.

Amidino derivatives and their use as thrombin inhibitors

There is provided compounds of formula I, wherein R1, R2, R3, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

1,3-Dimethoxy-5-methylene-1,3-cyclohexadiene Compounds with Leaving Groups at C6: Generation, Solvolytic Reactivity, and Their Importance in the Photochemistry of 3,5-Dimethoxybenzyl Derivatives

The photochemistry of 3,5-dimethoxybenzyl compounds with the leaving groups acetate (1a), chloride (1b), bromide (1c), iodide (1d), diethyl phosphate (1e), and trimethylamine (1f), as the chloride, was examined by both product studies and flash photolysis. The isomeric triene, 5-methylene-1,3-cyclohexadiene derivative was observed for the acetate (2a), diethyl phosphate (2e) and trimethylammonium chloride (2f). The solvolysis of these derivatives, 2, was examined in alcohol solvents and the rate correlation with YOTS values gave m = 0.47 (2a) and 0.63 (2e), suggesting SN1 reactivity but with an early transition state. Quantum yields for formation of 2a and 2e indicated that these trienes play only a minor role (～16%) in the overall photochemistry of the corresponding arylmethyl substrates.