5177-14-0

Basic information

• Product Name: 2-chloro-N,6-dimethyl-5-nitropyrimidin-4-amine
• Synonyms: 2-Chloro-N,6-dimethyl-5-nitropyrimidin-4-amine; 4-pyrimidinamine, 2-chloro-N,6-dimethyl-5-nitro-
• CAS NO: 5177-14-0
• Molecular Formula: C₆H₇ClN₄O₂
• Molecular Weight: 202.5984
• Mol File: 5177-14-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 385.6°C at 760 mmHg
• Flash Point: 187°C
• Density: 1.496g/cm³
• Vapor Pressure: 3.76E-06mmHg at 25°C
• Refractive Index: 1.632
• CAS DataBase Reference: 2-chloro-N,6-dimethyl-5-nitropyrimidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N,6-dimethyl-5-nitropyrimidin-4-amine(5177-14-0)
• EPA Substance Registry System: 2-chloro-N,6-dimethyl-5-nitropyrimidin-4-amine(5177-14-0)

Safety Data

• Hazardous Substances Data: 5177-14-0(Hazardous Substances Data)

Upstream product

• 13162-26-0 2,4-dichloro-6-methyl-5-nitropyrimidine 
• 74-89-5 methylamine 

Relevant articles and documents

Discovery of new thienopyrimidine derivatives as potent and orally efficacious phosphoinositide 3-kinase inhibitors

A series of new thienopyrimidine derivatives has been discovered as potent PI3K inhibitors. The systematic SAR studies for these analogues are described. Among them, 8a and 9a exhibit nanomolar enzymatic potencies and sub-micromolar cellular anti-prolifer