51779-95-4

Basic information

• Product Name: 1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
• Synonyms: PHOSPHATIDYLCHOLINE DIERUCOYL;1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-DIERUCOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;22:1 PC (CIS);DIC221PC;Dierucoyllecithin;L-Dierucoyl lecithin;(7R,22Z)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[[(13Z)-1-oxo-13-docosen-1-yl]oxy]-3,5,9-trioxa-4-phosphahentriacont-22-en-1-aminium 4-oxide, inner salt
• CAS NO: 51779-95-4
• Molecular Formula: C52H100NO8P
• Molecular Weight: 898.33
• Mol File: 51779-95-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 480 °C
• Appearance: /
• Storage Temp.: ?20°C
• Solubility: Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(51779-95-4)
• EPA Substance Registry System: 1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE(51779-95-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 51779-95-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is used as a component in the preparation of model membranes, such as the T-cell (LM3) model, for studying lipid dynamics and the effects of cholesterol on these dynamics. This application is crucial for understanding the behavior of various drugs and their interactions with cell membranes, which can lead to the development of more effective pharmaceuticals.
Used in Biomedical Research:
In the field of biomedical research, 1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is used as a key component in the generation of artificial membranes. These membranes serve as valuable tools for investigating the properties and functions of biological membranes, as well as for testing the efficacy and safety of potential therapeutic agents.
Used in Drug Delivery Systems:
1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE can also be utilized in the development of drug delivery systems, such as liposomes and micelles, which can improve the bioavailability and targeting of therapeutic agents. These systems can enhance the delivery of drugs to specific cells or tissues, reducing side effects and increasing the overall effectiveness of the treatment.

Biochem/physiol Actions

Phosphatidylcholine (PC) is capable of forming a strong bilayer.

Relevant articles and documents

Method for producing liposomes with increased percent of compound encapsulated

The efficiency of encapsulating a drug into a liposomal formulation is increased by use of a lipid having a carbon chain containing from about 13 to about 28 carbons during preparation of the liposomes. Preferably the liposomes are multivesicular liposomes.