51787-80-5

Basic information

• Product Name: δ-Hydroxy-δ-bis(p-fluorophenyl)butyl chloride
• Synonyms: δ-Hydroxy-δ-bis(p-fluorophenyl)butyl chloride
• CAS NO: 51787-80-5
• Molecular Weight: 296.744
• Mol File: 51787-80-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: δ-Hydroxy-δ-bis(p-fluorophenyl)butyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: δ-Hydroxy-δ-bis(p-fluorophenyl)butyl chloride(51787-80-5)
• EPA Substance Registry System: δ-Hydroxy-δ-bis(p-fluorophenyl)butyl chloride(51787-80-5)

Safety Data

• Hazardous Substances Data: 51787-80-5(Hazardous Substances Data)

Upstream product

• 3874-54-2 4-(4-fluorophenyl)-4-oxo-n-butyl chloride 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 352-13-6 4-flourophenylmagnesium bromide 

Downstream Products

• 77294-02-1 2-[4,4-Bis-(4-fluoro-phenyl)-but-3-enyl]-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole 
• 3311-94-2 4,4-bis(4-fluorophenyl)-3-butenyl chloride 

Relevant articles and documents

Agents Acting on CNS: Part XXX - Synthesis of 2-Substituted 1,2,3,4,6,7,12,12a-Octahydropyrazinopyrido-indoles

A number of 2-substituted pyrazinopyridoindoles (3,6-12) have been prepared by the condensation of 1,2,3,4,6,7,12,12a-octahydropyrazinopyridoindole (1) with appropriate halogen compounds.Treatment of 1 with ethylene oxide gives 4 which on condensation with p-fluorobenzoyl chloride yields 5.The corresponding 2-γ-(p-fluorobenzoyl)propyl-6-oxo-octahydropyrazinopyridoindole (14) is prepared by the oxidation of 1 with mercuric acetate followed by condensation of the resulting 6-oxo derivative (13) with γ-chloro-p-fluorobutyrophenone. 1-Oxo-2-substituted-pyrazinopyridoindoles (16-18) are prepared by the reaction of ethylene oxide on methyl 1,2,3,4-tetrahydropyridoindole-3-carboxylate followed by condensation of the resulting oxazino derivative (15) with amines.These compounds show tranquillizing, anti-inflammatory and diuretic activities.

Neurotropic and psychotropic agents. LXVII. 1 [4,4 bis(4 fluorophenyl)butyl] 4 hydroxy 4 (3 trifluoromethyl 4 chlorophenyl)piperidine and related compounds: new synthetic approaches

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