518-20-7 Usage
Description
PYRANOCOUMARIN is a type of coumarin compound known for its antioxidant properties. It is derived from various plant sources and has been a subject of interest due to its potential applications in different industries.
Uses
Used in Pharmaceutical Industry:
PYRANOCOUMARIN is used as a pharmaceutical compound for its antioxidant activity. It is particularly useful in studying the antioxidant activity of different types of coumarin compounds via an in-silico model of DPPH (2,2-diphenyl-1-picrylhydrazyl). This helps in understanding the potential therapeutic applications of PYRANOCOUMARIN in various health-related conditions.
Used in Chemical Research:
PYRANOCOUMARIN serves as a valuable compound in chemical research, specifically in the study of antioxidant properties and their implications in various chemical reactions and processes. Its unique structure and properties make it an essential component in the development of new drugs and therapies.
Used in Antioxidant Studies:
PYRANOCOUMARIN is used as a research tool for understanding the antioxidant mechanisms and their role in preventing cellular damage caused by free radicals. This knowledge can be applied to develop more effective antioxidants and treatments for various diseases and conditions related to oxidative stress.
Check Digit Verification of cas no
The CAS Registry Mumber 518-20-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 518-20:
(5*5)+(4*1)+(3*8)+(2*2)+(1*0)=57
57 % 10 = 7
So 518-20-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H18O4/c1-20(22-2)12-15(13-8-4-3-5-9-13)17-18(24-20)14-10-6-7-11-16(14)23-19(17)21/h3-11,15H,12H2,1-2H3
518-20-7Relevant articles and documents
New selective cyclooxygenase-2 inhibitors from cyclocoumarol: Synthesis, characterization, biological evaluation and molecular modeling
Rayar, Anita Marie,Lagarde, Nathalie,Martin, Frederique,Blanchard, Florent,Liagre, Bertrand,Ferroud, Clotilde,Zagury, Jean-Fran?ois,Montes, Matthieu,Sylla-Iyarreta Veitía, Maité
, p. 577 - 587 (2018/02/10)
In this work, a serie of cyclocoumarol derivatives was designed, synthesized, characterized and studied for their potentialities as selective inhibitors of COX-2. All target compounds have been screened for their anti-inflammatory activity by the assay of PGE2 production. Among them, compound 5d exhibited the most potent inhibitory activity with a PGE2 inhibition compared to NS-398 (79% and 88% respectively) and showed non-inhibitory activity towards the COX-1 enzyme. Docking studies revealed the capacity of this compound to occupy the selective COX-2 cavity establishing additional hydrogen bonds between the oxygen of the methoxy group and the His90 and Arg513 of the binding site of the enzyme.
High-yield synthesis of warfarin and its phenolic metabolites: New compounds
Buch,Trager
, p. 830 - 831 (2007/10/02)
A novel synthesis of warfarin and phenolic warfarin metabolites is presented which results in higher yields than previous methods.