51804-15-0

Basic information

• Product Name: 4-carboxyphenyl 4-methylbenzenesulfonate
• Synonyms: 4-carboxyphenyl 4-methylbenzenesulfonate
• CAS NO: 51804-15-0
• Molecular Weight: 292.312
• Mol File: 51804-15-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-carboxyphenyl 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-carboxyphenyl 4-methylbenzenesulfonate(51804-15-0)
• EPA Substance Registry System: 4-carboxyphenyl 4-methylbenzenesulfonate(51804-15-0)

Safety Data

• Hazardous Substances Data: 51804-15-0(Hazardous Substances Data)

Upstream product

• 4124-41-8 p-toluenesulfonylanhydride 
• 99-96-7 4-hydroxy-benzoic acid 
• 51207-43-3 methyl 4-(tosyloxy)benzoate 
• 24962-55-8 4-hydroxybenzaldehyde 4-methylbenzenesulfonate ester 
• 18414-58-9 diphenylmethylsilanecarboxylic acid 
• 84672-48-0 2-bromophenyl 4-methylbenzenesulfonate 
• 590-29-4 potassium formate 
• 6324-15-8 toluene-4-sulfonic acid 4-bromo-phenyl ester 

Downstream Products

• 64675-83-8 4-(toluene-4-sulfonyloxy)-benzoyl chloride 
• 51207-43-3 methyl 4-(tosyloxy)benzoate 
• 640-60-8 toluene-4-sulfonic acid phenyl ester 
• 1345403-81-7 cyclohex-2-enyl 4-(tosyloxy)benzoate 
• 1293362-53-4 toluenesulfonic acid-4-[6-methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophene-3-carbonyl]-phenyl ester 
• 1284251-49-5 C₁₈H₁₈O₇S 
• 103281-39-6 4-(toluene-4-sulfonyloxy)-benzoic acid-[4-(toluene-4-sulfonyloxy)-benzyl ester] 
• 106473-33-0 4-carbamoylphenyl-4-methylbenzenesulfonate 

Relevant articles and documents

Cleavage of Carboxylic Esters by Aluminum and Iodine

A one-pot procedure for deprotecting carboxylic esters under nonhydrolytic conditions is described. Typical alkyl carboxylates are readily deblocked to the carboxylic acids by the action of aluminum powder and iodine in anhydrous acetonitrile. Cleavage of lactones affords the corresponding ω-iodoalkylcarboxylic acids. Aryl acetylates undergo deacetylation with the participation of the neighboring group. This method enables the selective cleavage of alkyl carboxylic esters in the presence of aryl esters.

Palladium-catalyzed synthesis of aromatic carboxylic acids with silacarboxylic acids

Aryl iodides and bromides were easily converted to their corresponding aromatic carboxylic acids via a Pd-catalyzed carbonylation reaction using silacarboxylic acids as an in situ source of carbon monoxide. The reaction conditions were compatible with a wide range of functional groups, and with the aryl iodides, the carbonylation was complete within minutes. The method was adapted to the double and selective isotope labeling of tamibarotene.