51814-17-6

Basic information

• Product Name: Ethyl 3-(((benzyloxy)carbonyl)-(2-ethoxy-2-oxoethyl)amino)propanoate
• Synonyms: Ethyl 3-(((benzyloxy)carbonyl)-(2-ethoxy-2-oxoethyl)amino)propanoate;3-[(N-benzyloxycarbonylethoxycarbonyl)methylamino]propanoic acid ethyl ester;Ethyl 3-[(N-benzyloxycarbonylethoxycarbonyl)methylamino]propanoate;BENZYL 2-(ETHOXYCARBONYL)ETHYL (ETHOXYCARBONYL)METHYLCARBAMATE
• CAS NO: 51814-17-6
• Molecular Formula: C₁₇H₂₃NO₆
• Molecular Weight: 337
• Mol File: 51814-17-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 445.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.169±0.06 g/cm3(Predicted)
• PKA: -1.87±0.70(Predicted)
• CAS DataBase Reference: Ethyl 3-(((benzyloxy)carbonyl)-(2-ethoxy-2-oxoethyl)amino)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3-(((benzyloxy)carbonyl)-(2-ethoxy-2-oxoethyl)amino)propanoate(51814-17-6)
• EPA Substance Registry System: Ethyl 3-(((benzyloxy)carbonyl)-(2-ethoxy-2-oxoethyl)amino)propanoate(51814-17-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 51814-17-6(Hazardous Substances Data)

Usage

General Description

Ethyl 3-(((benzyloxy)carbonyl)-(2-ethoxy-2-oxoethyl)amino)propanoate is a complex chemical compound with the molecular formula C20H25NO7. It is a synthetic organic molecule with a carbonyl group, an ethyl group, and an amino group. The compound is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and drug intermediates. It is also used as a reagent in organic synthesis and chemical research, due to its versatile functional groups and reactivity. The compound has potential applications in the development of novel pharmaceuticals and bioactive molecules due to its unique structure and properties.

Upstream product

• 140-88-5 ethyl acrylate 
• 623-33-6 glycine ethyl ester hydrochloride 
• 501-53-1 benzyl chloroformate 
• 539-74-2 Ethyl 3-bromopropionate 
• 3783-61-7 diethyl 2-azabutane-1,4-dicarboxylate 

Downstream Products

• 296234-14-5 (2R,3S,1'S,2'S)-N-benzoxycarbonyl-2-(1'-hydroxy-2'-thiophenyl-3'-butenyl)-3-methoxymethyloxypyrrolidine 
• 296234-15-6 (2R,3S,1'R)-N-benzoxycarbonyl-2-(1',4'-dihydroxy-2'butenyl)-3-methoxymethyloxypyrrolidine 
• 296234-12-3 ethyl (2R,3S)-N-benzoxycarbonyl-3-methoxymethyloxypyrrolidine-2-carboxylate 
• 296234-13-4 (2R,3S)-N-benzoxycarbonyl-3-hydroxymethyl-3-methoxymethyloxypyrrolidine 
• 296234-11-2 (2R,3S)-N-benzoxycarbonyl-3-methoxymethyloxypyrrolidine-2-carboxaldehyde 
• 131270-20-7 ethyl (2R,3S)-N-benzoxycarbonyl-3-hydroxypyrrolidine-2-carboxylate 
• 51814-19-8 1-Benzyloxycarbonyl-4-ethoxycarbonyl-3-oxopyrrolidine 
• 51814-18-7 3-oxo-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-ethyl ester 

Relevant articles and documents

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A method for synthesizing cloth Sha Xing intermediate and its

The invention relates to a zabofloxacin intermediate and a synthetic method thereof. The synthetic method comprises the following steps: by adopting glycinate hydrochloride as a starting raw material, carrying out addition with ethyl acrylate, then cyclizing under an alkaline condition, and then carrying out methylolation reaction with formaldehyde under the alkaline condition; then reacting with methoxyamine hydrochloride into imine; and finally reacting with paratoluensulfonyl chloride into ester to obtain a target compound. The process disclosed by the invention has the advantages of easiness for raw material obtaining, low price, moderate yield and easiness for operation.

Synthesis and in-vitro activity of new 1β-methylcarbapenem derivatives as antibacterial agents

The synthesis of a new series of 1β-methylcarbapenems having pyrrolidine and piperidine moieties is described. Their in-vitro antibacterial activities against both Gram-positive and Gram-negative bacteria were tested and the effect of substituents on the pyrrolidine ring was investigated. A particular compound III b having an oxime-pyrrolidine moiety showed the most potent antibacterial activity.