518314-30-2

Basic information

• Product Name: 3-benzyloxy-5-methane-sulfonyloxy-5,6,7,8-tetrahydro-quinoline-4-carboxylic acid ethyl ester
• CAS NO: 518314-30-2
• Molecular Weight: 405.472
• Mol File: 518314-30-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-benzyloxy-5-methane-sulfonyloxy-5,6,7,8-tetrahydro-quinoline-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyloxy-5-methane-sulfonyloxy-5,6,7,8-tetrahydro-quinoline-4-carboxylic acid ethyl ester(518314-30-2)
• EPA Substance Registry System: 3-benzyloxy-5-methane-sulfonyloxy-5,6,7,8-tetrahydro-quinoline-4-carboxylic acid ethyl ester(518314-30-2)

Safety Data

• Hazardous Substances Data: 518314-30-2(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 518314-34-6 [3-benzyloxy-5-(4-dimethylaminomethyl-phenylsulfanyl)-5,6,7,8-tetrahydro-quinoline-4-yl]methanol 
• 518314-36-8 3-benzyloxy-5-(4-dimethylaminomethyl-phenylsulfanyl)-5,6,7,8-tetrahydro-quinoline-4-carbaldehyde 
• 518314-32-4 3-benzyloxy-5-(4-dimethylaminomethyl-phenylsulfanyl)-5,6,7,8-tetrahydro-quinoline-4-carboxylic acid ethyl ester 

Relevant articles and documents

Stereoselectivity in reactions of amino acids catalyzed by pyridoxal derivatives carrying rigidly-attached chirally-mounted basic groups - Transamination, racemization, decarboxylation, retro-aldol reaction, and aldol condensation

A tetrahydroquinoline ring was used to mount the critical functional groups of pyridoxal, and also two examples of rigidly held chirally mounted basic groups. They were able to selectively catalyze decarboxylation, aldol reaction, and retro-aldol reaction of amino acids rather than transamination, and with stereoselectivity. In the aldol reaction of glycine with acetaldehyde to synthesize threonine and allo-threonine, one of the catalysts reversed its stereoselectivity when the basic group was protonated. The observed stereoselectivities were all consistent with prediction.