51896-26-5

Basic information

• Product Name: 5-chloro-2-methylbenzenesulfonamide
• CAS NO: 51896-26-5
• Molecular Formula: C₇H₈ClNO₂S
• Molecular Weight: 205.6619
• Mol File: 51896-26-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 372.2°C at 760 mmHg
• Flash Point: 178.9°C
• Density: 1.402g/cm³
• Vapor Pressure: 9.77E-06mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 5-chloro-2-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-methylbenzenesulfonamide(51896-26-5)
• EPA Substance Registry System: 5-chloro-2-methylbenzenesulfonamide(51896-26-5)

Safety Data

• Hazardous Substances Data: 51896-26-5(Hazardous Substances Data)

Upstream product

• 106-43-4 para-chlorotoluene 
• 34981-38-9 5-chloro-2-methyl-benzene-sulfonyl chloride 
• 118-88-7 4-amino-toluene-2-sulfonic acid 

Downstream Products

• 46149-10-4 6-chloro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide 
• 1254305-59-3 C₁₆H₁₀Cl₂F₃N₃O₃S 

Relevant articles and documents

Some new 1,2-benzothiazine derivatives with analgesic and anti-inflammatory activities

Twenty-three new 7-halo-4-hydroxy-2H(or alkyl)-N-(3-aralkyl-2-thio-l-hydantoinyl)-2H- 1,2-benzothiazine-3-carboxamide 1,1-dioxide derivatives were synthesized through the condensation of 7-halo-4-hydroxy-2H(or alkyl)-1,2-benzothiazine-3-carboxylic acid methyl ester 1,1-dioxides with 1-amino-2-thio-3-aralkyl-imidazolidine-4-one. The analgesic and anti-inflammatory activities of the synthesized compounds were investigated by acetic acid-induced writhing syndrome and carrageenan rat paw edema tests. In analgesic activities most compounds exhibited higher activities than acetylsalicylic acid, but in antiinflammatory activities most compounds except compounds 24, 36, 39 showed lower activities than indometacin.