518987-37-6

Basic information

• Product Name: 6-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE
• Synonyms: 6-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE;6-METHOXY-1H-INDAZOLE-3-CARBOXALDEHYDE;6-Methoxy-1H-indazole-3-carboxyaldehyde;1H-Indazole-3-carboxaldehyde,6-Methoxy-
• CAS NO: 518987-37-6
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.17
• Product Categories: Indazole
• Mol File: 518987-37-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 200.1-200.2 °C
• Boiling Point: 391.67 °C at 760 mmHg
• Flash Point: 190.675 °C
• Appearance: /
• Density: 1.347 g/cm³
• PKA: 12.34±0.40(Predicted)
• CAS DataBase Reference: 6-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE(518987-37-6)
• EPA Substance Registry System: 6-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE(518987-37-6)

Safety Data

• Hazardous Substances Data: 518987-37-6(Hazardous Substances Data)

Usage

General Description

6-Methoxy-1H-indazole-3-carbaldehyde is a chemical compound that belongs to the class of indazole derivatives. It is a yellow solid that is commonly used as a building block in organic synthesis and pharmaceutical research. 6-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE has potential pharmacological properties and has been studied for its potential biological activities. It possesses a methoxy group and a carbaldehyde moiety, which make it a versatile intermediate in the synthesis of various compounds. Additionally, it has been investigated for its potential therapeutic applications in the treatment of various diseases.

Upstream product

• 7746-29-4 6-methoxy-3-methyl-1H-indazole 
• 74457-86-6 1-(2-fluoro-4-methoxyphenyl)-1-ethanone 
• 691900-70-6 tert-butyl-6-methoxy-3-methyl-1-indazole-carboxylate 
• 518990-36-8 6-methoxy-1H-indazole-3-carboxylic acid 
• 518990-05-1 C₉H₁₀N₂O₂ 
• 691900-68-2 C₁₄H₁₆Br₂N₂O₃ 

Downstream Products

• 889134-30-9 (6-methoxy-1H-indazol-3-yl)-(3,4,5-trimethoxyphenyl)methanone 
• 889134-39-8 C₁₈H₂₀N₂O₅ 

Relevant articles and documents

Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents

Utilizing scaffold-hopping drug-design strategy, we sought to identify a backup drug candidate for BPR0L075 (1), an indole-based anticancer agent. For this purpose, 5,6-fused bicyclic heteroaromatic scaffolds were designed and synthesized through shufflin

OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION

This invention relates to potent potassium channel blocker compounds of structural Formula I or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.

Ophthalmic compositions for treating ocular hypertension

This invention relates to potent potassium channel blocker compounds of Formula I or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relate