5193-84-0

Basic information

• Product Name: 4,6-Dihydroxy-5-methoxypyrimidine
• Synonyms: 4,6-DIHYDROXY-5-METHOXYPYRIMIDINE;5-Methoxy-4,6-pyrimidinediol;5-METHOXY-PYRIMIDINE-4,6-DIOL;4(1H)-Pyrimidinone, 6-hydroxy-5-methoxy- (9CI);6-Hydroxy-5-methoxy-4(1H)-pyrimidinone;4(3H)-Pyrimidinone,6-hydroxy-5-methoxy-;5-methoxy-1H-pyrimidine-4,6-dione
• CAS NO: 5193-84-0
• Molecular Formula: C₅H₆N₂O₃
• Molecular Weight: 142.11
• Product Categories: PYRIMIDINE;APIs & Intermediate;Pyridines, Pyrimidines, Purines and Pteredines;Pyrazines, Pyrimidines & Pyridazines;Heterocyclic Compounds;Pyrazines, Pyrimidines & Pyridazines
• Mol File: 5193-84-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 341-345 °C
• Boiling Point: 336.4 °C at 760 mmHg
• Flash Point: 157.3 °C
• Appearance: /
• Density: 1.468 g/cm³
• Vapor Pressure: 5.76E-05mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: 2-8°C
• PKA: 4.90±0.10(Predicted)
• CAS DataBase Reference: 4,6-Dihydroxy-5-methoxypyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Dihydroxy-5-methoxypyrimidine(5193-84-0)
• EPA Substance Registry System: 4,6-Dihydroxy-5-methoxypyrimidine(5193-84-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 5193-84-0(Hazardous Substances Data)

Usage

General Description

4,6-Dihydroxy-5-methoxypyrimidine is a chemical compound with the molecular formula C6H6N2O3. It is a pyrimidine derivative with two hydroxyl groups and one methoxy group attached to the pyrimidine ring. This chemical is commonly used in pharmaceutical research and drug development as it has potential therapeutic applications. It has been studied for its antioxidant, anti-inflammatory, and anti-cancer properties, and it is also used as a precursor in the synthesis of various pharmaceutical compounds. Additionally, 4,6-Dihydroxy-5-methoxypyrimidine has been investigated for its potential as a chelating agent and in the development of metal complexes for various industrial applications.

InChI:InChI=1/C5H6N2O3/c1-10-3-4(8)6-2-7-5(3)9/h2H,1H3,(H2,6,7,8,9)

Upstream product

• 5018-30-4 dimethyl methoxymalonate 
• 3473-63-0 formamidine acetic acid 

Downstream Products

• 5018-38-2 4,6-dichloro-5-methoxypyrimidine 
• 141071-86-5 5-methoxy-4-piperazin-1-yl-pyrimidine 
• 141071-88-7 4-(5-Methoxy-4-pyrimidinyl)-2-methylpiperazine 

Relevant articles and documents

MODULATORS OF METABOLISM AND THE TREATMENT OF DISORDERS RELATED THERETO

The present invention relates to 4-[5-Methoxy-6-(2-methyl-6-[1,2,4]triazol-1-yl-pyridin-3-ylamino)-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester, pharmaceutically acceptable salts, solvates and hydrates thereof that are modulators of glucose metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity. (Formula I)

Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same

A subject of the invention is the compounds of formula (I): in which R1, R2, R3, R4 and G have the meanings indicated in the description, their preparation process, their use as medicaments having an antagonist activity on the vitronectin receptor and the pharmaceutical compositions containing them.

INDOLYLALKYL DERIVATIVES OF PYRIMIDINYLPIPERAZINE FOR TREATING VASCULAR HEADACHE

A series of novel indol-3-ylalkyl derivatives of alkoxypyrimidinylpiperazines are disclosed as Formula I. STR1 These compounds are intended to be useful agents for alleviation of vascular headache on the basis of their potent affinity and agonist activity at 5-HT1D binding sites.