51957-36-9

Basic information

• Product Name: 2-PIPERIDINOPYRIMIDINE
• Synonyms: 2-N-piperidinopyrimidine
• CAS NO: 51957-36-9
• Molecular Formula: C9H13N3
• Molecular Weight: 163.22
• Mol File: 51957-36-9.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-PIPERIDINOPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PIPERIDINOPYRIMIDINE(51957-36-9)
• EPA Substance Registry System: 2-PIPERIDINOPYRIMIDINE(51957-36-9)

Safety Data

• Hazardous Substances Data: 51957-36-9(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 1722-12-9 2-chloropyrimidine 
• 64-17-5 ethanol 
• 4595-60-2 2-bromopyrimidine 
• 14080-23-0 2-cyanopyrimidine 
• 2508-29-4 5-hydroxypentylamine 

Relevant articles and documents

Fluorescence studies of selected 2-alkylaminopyrimidines

The reactions of 2-chloropyrimidine with methylamine, ethylamine and piperidine gave the corresponding 2-N-methylamino-, 2-N-ethylamino- and 2N-piperidinopyrimidines, respectively. The fluorescence properties of these alkylamino derivatives in chloroform, ethyl acetate, carbon tetrachloride, acetone, ether, ethanol and methanol were studied. All the alkylamino derivatives showed the highest fluorescence intensity in polar protic solvents; thus 2-N-methylaminopyrimidine (highest fluorescence intensity at 377 nm when excited at 282 nm) and 2-N-ethylaminopyrimidine (highest fluorescence intensity at 375 nm, when excited at 286 nm) showed the highest fluorescence in methanol. In ethanol, 2-N-piperidinopyrimidine showed a fluorescence peak at 403 nm when excited at 360 nm and in chloroform it fluoresced at 392 nm when excited at 356 nm.

Decyanative Cross-Coupling of Cyanopyrimidines with O-, S-, and N-Nucleophiles: A Route to Alkoxylpyrimidines, Aminopyrimidines and Alkylthiopyrimidines

The transition metal-free cross-coupling reactions of cyanopyrimidines with aliphatic alcohols, thiols (or S-alkylisothiourea salts) and amines, giving the corresponding alkoxylpyrimidines, aminopyrimidines, and alkylthiopyrimidines, are reported. Prelimi

Cu(II)-catalyzed C-N coupling of (hetero)aryl halides and N-Nucleophiles promoted by α-benzoin oxime

We first reported the new application of a translate metal chelating ligand α-benzoin oxime for improving Cu-catalyzed C-N coupling reactions. The system could catalyse coupling reactions of (hetero)aryl halides with a wide of nucleophiles (e.g., azoles, piperidine, pyrrolidine and amino acids) in moderate to excellent yields. The protocol allows rapid access to the most common scaαolds found in FDA-approved pharmaceuticals.