51985-06-9

Basic information

• Product Name: 3-Isopropenylphenol
• Synonyms: 3-Isopropenylphenol
• CAS NO: 51985-06-9
• Molecular Formula: C₉H₁₀O
• Molecular Weight: 134.18
• Mol File: 51985-06-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Isopropenylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isopropenylphenol(51985-06-9)
• EPA Substance Registry System: 3-Isopropenylphenol(51985-06-9)

Safety Data

• Hazardous Substances Data: 51985-06-9(Hazardous Substances Data)

Upstream product

• 121-71-1 3-Hydroxyacetophenone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 13387-60-5 3-(2-hydroxy-2-propyl)-1-(2-hydroperoxy-2-propyl)benzene 
• 7765-97-1 meta-hydroxy-α,α-dimethylbenzyl alcohol 
• 618-45-1 3-isopropylhydroxybenzene 
• 51985-05-8 acetic acid-(3-isopropenyl-phenyl ester) 

Downstream Products

• 591-27-5 m-Hydroxyaniline 
• 99777-70-5 3-methyl-1-(phenylamino)-1H-indol-5-ol 
• 25108-57-0 3-(1-methylethenyl)anisole 
• 19102-16-0 (3-isopropenyl-phenoxy)-acetic acid 

Relevant articles and documents

OH-directed alkynylation of 2-vinylphenols with ethynyl benziodoxolones: A fast access to terminal 1,3-enynes

The first direct alkynylation of 2-vinylphenols was developed. The rationally optimized hypervalent iodine reagent TIPS-EBX in combination with [(CpRhCl2)2] as a C-H-activating transition metal catalyst enables the construction of a variety of highly substituted 1,3-enynes in high yields of up to 98 %. This novel C-H activation method shows excellent chemoselectivity and exclusive (Z)-stereoselectivity, and it is also remarkably mild and tolerates a variety of functional groups. Furthermore, synthetic modifications of the resulting 1,3-enynes were demonstrated. To our knowledge, this is the first example for an OH-directed C-H alkynylation with hypervalent iodine reagents.