51997-49-0Relevant articles and documents
A novel carbazole derivative, MHY407, sensitizes cancer cells to doxorubicin-, etoposide-, and radiation treatment via DNA damage
Yoon, Sungpil,Kim, Ju-Hwa,Lee, Young Ju,Ahn, Mee Young,Choi, Gayoung,Kim, Won Ki,Yang, Zunhua,Lee, Hye Jin,Moon, Hyung Ryong,Kim, Hyung Sik
, p. 24 - 31 (2012)
In this study, we synthesized a novel carbazole derivative, MHY407, as a sensitizer of cancer cells to increase DNA damage. We then evaluated the anticancer effects of MHY407 and identified the molecular mechanism for the sensitization of breast cancer ce
STORE OVERLOAD-INDUCED CALCIUM RELEASE INHIBITORS AND METHODS FOR PRODUCING AND USING THE SAME
-
Sheet 2/7, (2015/03/16)
The present invention provides compounds having store overload-induced Ca2+ release (SOICR) inhibitory activity and methods for producing and using the same. In particular, compounds of the invention is of the formula: R1-X1-L-X2-R2, wherein R1, X1, L, X2, and R2 are those defined herein.