52054-41-8

Basic information

• Product Name: 1,3-Benzenedicarbonitrile, 4-nitro-
• CAS NO: 52054-41-8
• Molecular Formula: C8H3N3O2
• Molecular Weight: 173.131
• Mol File: 52054-41-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-Benzenedicarbonitrile, 4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenedicarbonitrile, 4-nitro-(52054-41-8)
• EPA Substance Registry System: 1,3-Benzenedicarbonitrile, 4-nitro-(52054-41-8)

Safety Data

• Hazardous Substances Data: 52054-41-8(Hazardous Substances Data)

Usage

Appearance

Yellow solid

Usage

Precursor in the synthesis of various organic compounds and pharmaceuticals

Synonyms

4-nitro-1,3-phenylenedicyanide

Applications

Used in the synthesis of several organic compounds and in the pharmaceutical industry

Safety Precautions

Handle with care, use appropriate safety measures

Toxicity

Can be toxic if ingested or inhaled

Skin Irritation

May cause skin irritation upon contact

Upstream product

• 108-38-3 m-xylene 
• 89-87-2 2,4-dimethylnitrobenzene 
• 88678-15-3 4-nitroisophthalic acid dichloride 
• 65426-59-7 4-nitrobenzene-1,3-dicarboxylic acid diamide 
• 4315-09-7 4-nitroisophthalic acid 

Downstream Products

• 97510-14-0 4-(4-Cyano-phenylamino)-isophthalonitrile 
• 34133-58-9 4-hydroxy-isophthalonitrile 
• 123871-54-5 diethyl (α,α-dimethyl-o,p-dicynobenzyl)methylmalonate 
• 72214-06-3 o,p-dicyano-α-phenylsulfonylcumene 
• 72206-82-7 o,p-dicyano-α-phenylsulfmercaptocumene 
• 72206-83-8 2-(o,p-dicyanophenyl)-2,3-dimethyl-3-nitrobutane 
• 143057-10-7 bis(2,4-dicyanophenyl) ether 
• 34633-31-3 4-hydroxy-5-iodoisophthalonitrile 
• 34633-30-2 5-bromo-4-hydroxyisophthalonitrile 
• 118412-92-3 4-Phenylamino-isophthalonitrile 
• 19619-22-8 2,4-dicyanoaniline 
• 4387-30-8 4-chloro-1,3-benzenedicarbonitrile 
• 13520-07-5 4-morpholinoisophthalonitrile 

Relevant articles and documents

Water-induced fluorescence quenching of mono- and dicyanoanilines

Photophysical properties of monocyano- (2-, 3-, and 4-cyano) and dicyano- (3,4-, 3,5-, 2,3-, 2,4-, 2,5-, and 2,6-dicyano) anilines are investigated by fluorescence measurements. All the monocyanoanilines are virtually nonfluorescent in water (quantum yield 0.01); however, in nonaqueous solvents (cyclohexane, acetonitrile and ethanol), the fluorescence quantum yield is enhanced substantially. In contrast, dicyanoanilines investigated are highly fluorescent both in aqueous and nonaqueous environments. The photophysical data and MO calculations suggest that conformational changes in the amino group and variation of hydrogen-bonding interactions between the solute and solvent water upon electronic excitation are responsible for the water quenching in the monocyanoanilines.

Electron-Transfer Substitution Reactions: Facilitation by the Cyano Group

It is now clear that a cyano group facilitates electron-transfer substitution reactions.Of particular interest is the demonstration that electron-transfer chain substitution at a saturated carbon atom has been achieved in the absence of a nitro group.