52085-92-4

Basic information

• Product Name: 2,3-DIHYDRO-5-FLUORO-1H-INDEN-1-OL
• Synonyms: 2,3-DIHYDRO-5-FLUORO-1H-INDEN-1-OL;5-fluoro-2,3-dihydro-1H-inden-1-ol;1H-Inden-1-ol, 5-fluoro-2,3-dihydro-
• CAS NO: 52085-92-4
• Molecular Formula: C₉H₉FO
• Molecular Weight: 152.17
• Mol File: 52085-92-4.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2,3-DIHYDRO-5-FLUORO-1H-INDEN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-5-FLUORO-1H-INDEN-1-OL(52085-92-4)
• EPA Substance Registry System: 2,3-DIHYDRO-5-FLUORO-1H-INDEN-1-OL(52085-92-4)

Safety Data

• Hazardous Substances Data: 52085-92-4(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-5-fluoro-1H-inden-1-ol is a chemical compound with the molecular formula C9H9FO. It is a white to off-white solid that is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2,3-DIHYDRO-5-FLUORO-1H-INDEN-1-OL is classified as a fluorine-containing organic compound and is known for its potential applications as a building block in the production of various pharmaceuticals. Additionally, it can also be used in the synthesis of other organic compounds and as a research reagent in chemical and biochemical studies. Its unique structure and properties make it a valuable and versatile chemical in the field of organic chemistry and drug development.

Upstream product

• 347-93-3 3-chloro-4'-fluoropropiophenone 
• 462-06-6 fluorobenzene 
• 700-84-5 5-fluoro-1-indanone 

Downstream Products

• 52031-15-9 5-fluoro-1H-indene 
• 939760-59-5 C₉H₇FO 
• 1426653-99-7 3-amino-4-fluoro-N-((1R,2S)-5-fluoro-2-hydroxy-2,3-dihydro-1H-inden-1-yl)benzamide 
• 1075-11-2 6-fluoroisoquinoline 
• 915030-25-0 1-cyano-5-fluoroindane 
• 628732-48-9 5-fluoro-indan-1-carboxylic acid 
• 58485-67-9 1-chloro-5-fluoroindane 

Relevant articles and documents

Synthesis of Indole-Dihydroisoquinoline Sulfonyl Ureas via Three-Component Reactions

Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivatives. Using a differential protecting group strategy, products could be further derivatised. Synthesis of isoquinoline starting materials using several different methods is also described.

HISTONE DEMETHYLASE INHIBITORS

Provided herein are substituted pyrazolylpyridine, pyrazolylpyridazine, and pyrazolylpyrimidine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.

SUBSTITUTED PIPERAZINES AS CB1 ANTAGONISTS

Compounds of Formula (I): or pharmaceutically acceptable salts, solvates, or esters thereof, are useful in treating diseases or conditions mediated by CB1 receptors, such as metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, addiction (e.g., smoking cessation), gastrointestinal disorders, and cardiovascular conditions.