52096-79-4

Basic information

• Product Name: 2-(3-(Methylthio)propyl)isoindoline-1,3-dione
• Synonyms: 2-(3-(Methylthio)propyl)isoindoline-1,3-dione
• CAS NO: 52096-79-4
• Molecular Formula: C₁₂H₁₃NO₂S
• Molecular Weight: 235.30212
• Mol File: 52096-79-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(3-(Methylthio)propyl)isoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-(Methylthio)propyl)isoindoline-1,3-dione(52096-79-4)
• EPA Substance Registry System: 2-(3-(Methylthio)propyl)isoindoline-1,3-dione(52096-79-4)

Safety Data

• Hazardous Substances Data: 52096-79-4(Hazardous Substances Data)

Usage

General Description

2-(3-(Methylthio)propyl)isoindoline-1,3-dione is a chemical compound with a unique structure containing a isoindoline-1,3-dione core and a 2-(3-(methylthio)propyl) side chain. The methylthio group, which is a thioether functional group, is attached to the propyl side chain. 2-(3-(Methylthio)propyl)isoindoline-1,3-dione is commonly used in organic synthesis and pharmaceutical research due to its interesting chemical properties and potential medicinal applications. Its structure and functional groups make it a valuable intermediate for the synthesis of various organic compounds and pharmaceuticals. Additionally, it has been studied for its potential biological activities and therapeutic properties, making it an important compound in drug discovery and development.

Upstream product

• 5460-29-7 2-(3-bromopropyl)isoindole-1,3-dione 
• 5188-07-8 sodium thiomethoxide 
• 74-93-1 methylthiol 
• 13012-59-4 3-methylthiopropyl chloride 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 98184-57-7 2-<(3-Methylsulfinyl)propyl>-1H-isoindole-1,3(2H)-dione 
• 98184-58-8 2-<(3-Methylsulfonyl)propyl>-1H-isoindole-1,3(2H)-dione 
• 4104-45-4 3-methylthio-1-propanamine 

Relevant articles and documents

Method for preparing 3-methylthio propylamine

The invention provides a preparation method of 3-methylthio propylamine. The method is characterized in that under the effects of microwaves and ultrasonic waves, flavoring essence of 3-methylthio propyl alcohol capable of being easily obtained in China is used as a starting raw material; the reaction time is short; the total yield is relatively high. Under the effects of microwaves and ultrasonicwaves, firstly, 3-methylthio propyl alcohol and thionyl chloride react for 20 to 60 min under the back flow condition to prepare 3-methylthio-1-chloropropane, and the yield is greater than 95 percent; then, at 80 to 90 DEG C, the 3-methylthio-1-chloropropane and phthalimide potassium react for 0.5 to 2.5h to prepare N-3-methylthio propyl phthalimide, and the yield is greater than 94 percent; finally, the N-3-methylthio propyl phthalimide and hydrazine hydrate perform backflow reaction in absolute ethyl alcohol for 20 to 60min to prepare the 3-methylthio propylamine, and the yield is greater than 85 percent.

BIOTRANSFORMATION OF ORGANIC SULFIDES. PART 7. FORMATION OF CHIRAL ISOTHIOCYANATO SULFOXIDES AND RELATED COMPOUNDS BY MICROBIAL BIOTRANSFORMATION

The fungi Helminthosporium species NRRL 4671 and Mortierella isabellina ATCC 42613 have been used for the biotransformation of a series of isothiocyanatoalkyl methyl sulfides and their synthetic precursors, ω-(methylthio)alkylphthalimides.H. species gave predominantly (S) sulfoxides in all cases; M. isabellina gave (R) isothiocyanatoalkyl methyl sulfoxides, but in the case of two ω-(methylthio)alkylphthalimides substantial conversion of sulfoxide to sulfone resulted in the isolation of the former with predominant (S) configuration.A correction is made of the previously reported configurations of two biotransformation products (Tetrahedron: Asymmetry, 1994, 5, 1129).

Photochemistry of the Phthalimide System, 37. - Thiazacycloalkanols by Photocyclization of S-Substituted N-(Thioalkyl)phthalimides

N-Substituted phthalimides (1,2) possessing a terminal thioether function in their side chain were irradiated with a high-pressure mercury lamp to give a variety of thiazacycloalkanol derivatives (3,7,9-13,16,17) with favored γ-, δ-, ε-, and ζ-hydrogen abstractions (Table 1), in moderate to fairly good yields.