521-65-3 Usage
Description
Swerchirin, also known as the 5-O-methyl derivative of bellidifolin, is a member of the xanthone class. It is primarily isolated from the plants Centaurium erythraea and Swertia chirayita. Swerchirin exhibits hypoglycemic activity, making it a potential candidate for pharmaceutical applications related to blood sugar regulation.
Uses
Used in Pharmaceutical Industry:
Swerchirin is used as a hypoglycemic agent for its ability to regulate blood sugar levels. This application is particularly relevant for the development of treatments and medications for diabetes and other conditions involving blood sugar imbalances.
Used in Research and Development:
In addition to its direct pharmaceutical applications, swerchirin is also used as a research compound for studying the effects of xanthones on blood sugar regulation and their potential role in the development of new treatments for diabetes and related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 521-65-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 521-65:
(5*5)+(4*2)+(3*1)+(2*6)+(1*5)=53
53 % 10 = 3
So 521-65-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H12O6/c1-19-7-5-9(17)12-11(6-7)21-15-10(20-2)4-3-8(16)13(15)14(12)18/h3-6,16-17H,1-2H3
521-65-3Relevant articles and documents
Xanthone glycoside constituents of Swertia kouitchensis with α-glucosidase inhibitory activity
Wan, Luo-Sheng,Min, Qiu-Xia,Wang, Yong-Long,Yue, Yao-Dong,Chen, Jia-Chun
, p. 1248 - 1253 (2013/08/23)
Ten new xanthone glycosides, kouitchensides A-J (1-10), and 11 known analogues were isolated from an n-butanol fraction of Swertia kouitchensis. The structures of these glycosides were determined on the basis of extensive spectroscopic data interpretation and comparison with data reported in the literature. In an in vitro test, compounds 2, 4, 5, 6, 11, 12, and 13 (IC 50 values in the range 126 to 451 μM) displayed more potent inhibitory effects against α-glucosidase activity than the positive control, acarbose (IC50 value of 627 μM).