521985-18-2

Basic information

• Product Name: 2-(4-CBZ-PIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID
• Synonyms: 2-(4-CBZ-PIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID;6-(4-(benzyloxycarbonyl)piperazin-1-yl)pyridine-3-boronic acid;N-CBZ-6-(piperazin-1-yl)pyridin-3-ylboronic acid;4-(5-Borono-2-pyridinyl)-1-piperazinecarboxylic acid 1-(phenylmethyl) ester
• CAS NO: 521985-18-2
• Molecular Formula: C₁₇H₂₀BN₃O₄
• Molecular Weight: 341.173
• Mol File: 521985-18-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-CBZ-PIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CBZ-PIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID(521985-18-2)
• EPA Substance Registry System: 2-(4-CBZ-PIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID(521985-18-2)

Safety Data

• Hazardous Substances Data: 521985-18-2(Hazardous Substances Data)

Usage

Chemical class

Pyridine boronic acids

Structure

Pyridine ring attached to a boronic acid group and a piperazine group with a carbobenzyloxy (CBZ) substituent

Usage

Widely used in organic synthesis and medicinal chemistry

Biological activities

Known to have various biological activities

Potential applications

Development of pharmaceuticals or as a reagent in organic synthesis reactions

Further research

Studies and research may be conducted to explore its potential applications and properties

Upstream product

• 521985-16-0 1-benzyloxycarbonyl-4-(5-bromopyridin-2-yl)piperazine 
• 5419-55-6 Triisopropyl borate 

Relevant articles and documents

AMIDE DERIVATIVES AND DRUGS

The present invention provides an amide derivative represented by the following formula [1]: wherein n represents 0 or 1; X represents CR4 or N; Y represents CR6 or N; Z represents CR7 or N; R1 and R2 may be the same or different and each represents hydrogen, optionally substituted alkyl, acyl, optionally substituted aryl, or an optionally substituted aromatic heterocyclic group; R4, R5, R6 and R7 may be the same or different and each represents hydrogen, halogen, hydroxy, amino, alkyl, haloalkyl, alkoxy, monoalkylamino, dialkylamino, arylalkyl, cyano, or nitro; and R3 represents optionally substituted alkylamino, optionally substituted arylamino, or optionally substituted cyclic amino, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising them as an active ingredient. The compound of the present invention is useful as a TGF-β inhibitor.