5223-61-0Relevant articles and documents
Zr-catalyzed coupling reaction of alkyl halides, tosylates, and sulfates with β-phenethyl Grignard reagents via styrene-zirconate intermediates
Terao, Jun,Begum, Shameem Ara,Oda, Akihiro,Kambe, Nobuaki
, p. 1783 - 1786 (2007/10/03)
β-Phenethylmagnesium chlorides react with alkyl halides, tosylates, and sulfates in the presence of a catalytic amount of Cp2ZrCl 2 to afford 2-arylalkanes via alkylation of styrene-zirconate intermediates at the benzylic position. Competitive reaction using mixtures of alkyl halides (alkyl-X; X = F, Cl, Br) showed that the reactivities of the halides increase in the order of alkyl-Cl alkyl-F alkyl-Br with the relative rates of 1:19:428. Georg Thieme Verlag Stuttgart.