52329-99-4Relevant articles and documents
Acylation of Alkenes with the Aid of AlCl3 and 2,6-Dibromopyridine
Tanaka, Shinya,Kunisawa, Tsukasa,Yoshii, Yuji,Hattori, Tetsutaro
supporting information, p. 8509 - 8513 (2019/11/03)
Friedel-Crafts-type acylation of alkenes with acyl chlorides has been successfully conducted with a wide substrate scope by the combined use of AlCl3 and 2,6-dibromopyridine. Trisubstituted alkenes afford allylketones or vinylketones depending on the presence or absence of hydrogen atom(s) at the β-position to the acylation site, while monosubstituted alkenes exclusively afford vinylketones.
Olefination of ketones using a gold(III)-catalyzed Meyer-Schuster rearrangement
Engel, Douglas A.,Dudley, Gregory B.
, p. 4027 - 4029 (2007/10/03)
An atom-economical and efficient olefination strategy for ketones is described. Ethoxyacetylide addition followed by a gold-catalyzed Meyer-Schuster rearrangement affords α,β-unsaturated esters, generally in excellent overall yield from the starting ketones. The alkynophilicity of Au3+ promotes an interaction with the electron-rich acetylenes that catalyzes the Meyer-Schuster rearrangement selectively over other conceivable pathways.
Studies on the addition of Grignard reagents and metal hydrides to α-oxoketene N,S-acetals
Balu,Bhat,Ila,Junjappa
, p. 250 - 255 (2007/10/02)
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