52376-19-9

Basic information

• Product Name: 1-(4-bromo-2,5-dihydroxyphenyl)ethan-1-one
• Synonyms: 1-(4-bromo-2,5-dihydroxyphenyl)ethan-1-one
• CAS NO: 52376-19-9
• Molecular Weight: 231.046
• Mol File: 52376-19-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4-bromo-2,5-dihydroxyphenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromo-2,5-dihydroxyphenyl)ethan-1-one(52376-19-9)
• EPA Substance Registry System: 1-(4-bromo-2,5-dihydroxyphenyl)ethan-1-one(52376-19-9)

Safety Data

• Hazardous Substances Data: 52376-19-9(Hazardous Substances Data)

Upstream product

• 583-69-7 2-bromobenzene-1,4-diol 
• 64-19-7 acetic acid 
• 25245-34-5 1-bromo-2,5-dimethoxybenzene 

Downstream Products

• 120128-73-6 Acetic acid (1S,9S,10R,11R,12R)-4,12-bis-benzyloxy-5-bromo-11-iodo-1-methyl-8,13-dioxa-tricyclo[7.3.1.0^2,7]trideca-2,4,6-trien-10-yl ester 
• 120128-72-5 (1S,9S,10R,11S,12R)-4,12-Bis-benzyloxy-5-bromo-11-iodo-1-methyl-8,13-dioxa-tricyclo[7.3.1.0^2,7]trideca-2,4,6-trien-10-ol 
• 120128-71-4 C₂₆H₂₃BrO₅ 
• 88278-12-0 2-(2,5-dibenzyloxy-4-bromophenyl)-6-hydroxy-2-methyl-6H-pyran-3(2H)-one 
• 88289-39-8 1-(2,5-Bis-benzyloxy-4-bromo-phenyl)-1-furan-2-yl-ethanol 
• 88278-21-1 C₁₉H₁₅BrO₅ 
• 120147-77-5 C₁₉H₁₇BrO₅ 
• 88278-20-0 8-benzyloxy-9-bromo-6-methyl-2,6-epoxy-6H-1-benzoxec-3-en-5(2H)-one 
• 75859-16-4 5-Brom-2-acetyl-1,4-benzochinon 
• 88278-11-9 2,5-dibenzyloxy-4-bromoacetophenone 

Relevant articles and documents

2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The present disclosure features compounds of formula (l-a) and of formula (II) and pharmaceutical compositions thereof. The present disclosure further discloses the compounds of formula (I- a) and (II) and their compositions for use in methods of modulating nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as said compounds for use in methods of treating e.g.: ? proliferative diseases, such as e.g. cancer, benign neoplasms or angiogenesis, ? neurological diseases or disorders, such as e.g. Huntington's disease, ? autoimmune diseases or disorders, immunodeficiency diseases or disorders, lysosomal storage disease or disorder, cardiovascular diseases or disorders, metabolic diseases or disorders, respiratory diseases or disorders, renal diseases or disorders, or infectious diseases. Exemplary compounds are e.g. 2-(indazol-5-yl)-6-(piperidin-4-yl)-l,7- naphthyridine derivatives and similar compounds.

Synthesis of 2 bromo 5 acyl hydroquinones

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