52376-48-4

Basic information

• Product Name: 1-cyclohexylidene-3-phenylpropane
• Synonyms: 1-cyclohexylidene-3-phenylpropane
• CAS NO: 52376-48-4
• Molecular Weight: 200.324
• Mol File: 52376-48-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-cyclohexylidene-3-phenylpropane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclohexylidene-3-phenylpropane(52376-48-4)
• EPA Substance Registry System: 1-cyclohexylidene-3-phenylpropane(52376-48-4)

Safety Data

• Hazardous Substances Data: 52376-48-4(Hazardous Substances Data)

Upstream product

• 58749-30-7 (3-phenylpropane-1,1-diyl)bis(phenylsulfane) 
• 108-94-1 cyclohexanone 
• 1123-34-8 1-allyl-1-cyclohexanol 
• 139313-45-4 1-allylcyclohexyl acetate 
• 98-80-6 phenylboronic acid 
• 134134-76-2 (4,4-difluorobut-3-en-1-yl)benzene 
• 23708-48-7 pentamethylenebis(magnesium bromide) 
• 637-59-2 1-Bromo-3-phenylpropane 
• 303144-06-1 3-phenyl-1-(1-p-tolylsulfinylcyclohexyl)-1-propanol 
• 303143-99-9 1-(3-phenyl-1-phenylsulfinylpropyl)cyclohexanol 
• 37605-77-9 3-phenylpropyl phenyl sulfoxide 
• 104-53-0 3-phenyl-propionaldehyde 
• 303144-02-7 1-(1-acetoxycyclohexyl)-3-phenyl-1-phenylsulfinylpropane 
• 101100-11-2 1-(3-phenylpropyl)cyclohexanol 

Relevant articles and documents

Remote Arylative Substitution of Alkenes Possessing an Acetoxy Group via β-Acetoxy Elimination

Palladium-catalyzed remote arylative substitution was achieved for the reaction of arylboronic acids with alkenes possessing a distant acetoxy group to provide arylation products having an alkene moiety at the remote position. The use of β-acetoxy elimination as a key step in the catalytic cycle allowed for regioselective formation of unstabilized alkenes after chain walking. This reaction was applicable to various arylboronic acids as well as alkene substrates.

A sulfoxide version of the Julia-Lythgoe olefination: A new method for the synthesis of olefins from carbonyl compounds and sulfoxides with carbon-carbon coupling

Reaction of β-mesyloxy (or acetoxy) sulfoxides, derived from alkyl (or arylmethyl) phenyl sulfoxides and carbonyl compounds in two steps, with alkylmetals (n-BuLi, t-BuLi, or EtMgBr) at low temperature gave olefins in good to excellent yields. When the β-hydroxy sulfoxides derived from arylaldehydes were treated with mesyl chloride in the presence of triethylamine, the sulfoxides directly gave E-olefins in good yields. These reactions offer a sulfoxide version of the Julia-Lythgoe olefination. The reductive vicinal elimination was found to take place through the direct sulfoxide-metal exchange. The stereochemistry of the elimination was investigated and found to be stereospecific; however, the stereospecificity was found to be dependent on the substrates. (C) 2000 Elsevier Science Ltd.

Substituent Effects on the Intramolecular Photochemical Reactions of Phenyl-Ethenyl Non-conjugated Bichromophoric Systems

The effects of substitution on the photochemistry of phenyl-ethenyl bichromophoric systems are reported.Methyl substitution at the 2-, 3-, 5-, and 1,1,2-positions in the pentene moiety of 5-phenylpent-1-ene reduces both reaction efficiency and selectivity but in contrast to intramolecular analogues the photoreaction of 3-phenethylcyclohexene is comparable with that of the corresponding cyclopentene.Incorporation of ester units in the connecting unit between the chromophores or on the ethene inhibits intramolecular cyclisation as does the presence of para OMe, CN, or COMe groups in 5-phenylpent-1-ene.In contrast reaction selectivity and efficiency are greatly promoted by ortho Me or OMe groups and the products reflect exlusive 1,3-cycloaddition.The presence of a para Me group in 5-phenylpent-1-ene leads to specific 2,6-intramolecular cyclisation but the reaction of the meta-Me derivative leads to four products derived from 1,3- and 1,5-intramolecular cycloaddition.The observations are discussed in terms of mechanisms of arene-ethene photoreactions and preferred conformations of the bichromophores.