52399-43-6Relevant articles and documents
Sulfamylbenzoic acid derivatives
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, (2008/06/13)
Compounds of the general formula SPC1 In which R1 represents a straight or branched C1 -C6 alkyl, alkenyl or alkynyl radical, or a C1 -C3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; R2 stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, hydroxy, or lower alkoxy; X and Y stand for oxygen or sulphur; their salts and esters and methods for their preparation. The compounds of the invention possess an outstanding diuretic and saluretic activity with a very low excretion of potassium ions and a low toxicity.