52414-98-9

Basic information

• Product Name: 4-BROMO-2-METHYL-1-NITROBENZENE
• Synonyms: 4-BROMO-2-METHYL-1-NITROBENZENE;3-Bromo-6-nitrotoluene;4-Bromo-6-methylnitrobenzene;5-Bromo-1-methyl-2-nitrobenzene;4-Bromo-2-methyl-1-nitrobenzene, 4-Bromo-2-methylnitrobenzene;4-BroMo-2-Methylnitrobenzene;Benzene,4-broMo-2-Methyl-1-nitro-
• CAS NO: 52414-98-9
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.03
• EINECS: 230-481-4
• Mol File: 52414-98-9.mol
• Article Data: 9

Chemical Properties

• Melting Point: 53-55℃
• Boiling Point: 265℃
• Flash Point: 114℃
• Appearance: /
• Density: 1.615
• Vapor Pressure: 0.0074mmHg at 25°C
• Refractive Index: 1.6120 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-BROMO-2-METHYL-1-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-METHYL-1-NITROBENZENE(52414-98-9)
• EPA Substance Registry System: 4-BROMO-2-METHYL-1-NITROBENZENE(52414-98-9)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R20/21/22:; R36/37/38:
• Safety Statements: S22:; S26:; S36/37/39:
• Hazardous Substances Data: 52414-98-9(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-methyl-1-nitrobenzene is a chemical compound with the molecular formula C7H7BrNO2. It is a pale yellow, odorless solid that is mainly used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. This chemical is known to be toxic and harmful if swallowed or inhaled, and may cause irritation to the skin and eyes upon contact. It is also considered to be a potential environmental hazard due to its toxicity to aquatic organisms. Overall, 4-Bromo-2-methyl-1-nitrobenzene is a versatile but potentially hazardous compound that requires careful handling and disposal.

InChI:InChI=1/C7H6BrNO2/c1-5-4-6(9(10)11)2-3-7(5)8/h2-4H,1H3

Upstream product

• 591-17-3 meta-bromotoluene 
• 611-23-4 2-nitrosotoluene 
• 108-44-1 1-amino-3-methylbenzene 
• 108-39-4 3-methyl-phenol 
• 583-75-5 4-Bromo-2-methylaniline 
• 611-05-2 4-nitro-3-methylaniline 

Downstream Products

• 60326-45-6 (3-methyl-4-nitrophenyl)phenylthioether 
• 88070-23-9 bis-(4-amino-3-methyl-phenyl)-disulfide 
• 583-75-5 4-Bromo-2-methylaniline 
• 105205-48-9 [(E)-2-(5-bromo-2-nitro-phenyl)-vinyl]-dimethyl-amine 
• 35287-42-4 4-bromo-2-(bromomethyl)-1-nitrobenzene 
• 17403-17-7 (5-bromo-2-nitro-phenyl)-pyruvic acid 
• 53258-92-7 p-nitro-m-methylphenyl p-tolyl sulfide 
• 6950-43-2 5-bromo-2-nitrobenzoic acid 
• 837392-60-6 5-bromo-2-(trifluoromethyl)-1H-indole 
• 112768-01-1 4-bromo-1-nitro-2-vinylbenzene 

Relevant articles and documents

Nitration of deactivated aromatic compounds via mechanochemical reaction

A variety of deactivated arenes were nitrated to their corresponding nitro derivatives in excellent yields under high-speed ball milling condition using Fe(NO3)3·9H2O/P2O5 as nitrating reagent. A radical involved mechanism was proposed for this facial, eco-friendly, safe, and effective nitration reaction.

Highly efficient Sandmeyer reaction on immobilized CuI/CuII-based catalysts

Highly effective embodiment of Sandmeyer reaction has been revealed for Cu-based catalysts incorporating ionic liquid on Silochrom support. The most active catalyst (TOF = = 4000–8000 h–1) contains comparable amounts of cuprous and cupric chloride anions. The reported method allows one to carry out the reaction for anilines in the one-pot mode.

ANTIVIRAL AGENTS

Disclosed are compounds and compositions of Formula, (I) and their uses for treating Flaviviridae family virus infections.