52421-65-5

Basic information

• Product Name: Benzenecarbothioamide, N-[(dimethylamino)methylene]- (9CI)
• Synonyms: Benzenecarbothioamide, N-[(dimethylamino)methylene]- (9CI)
• CAS NO: 52421-65-5
• Molecular Formula: C₁₀H₁₂N₂S
• Molecular Weight: 192.28068
• Product Categories: THIOAMIDE
• Mol File: 52421-65-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenecarbothioamide, N-[(dimethylamino)methylene]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarbothioamide, N-[(dimethylamino)methylene]- (9CI)(52421-65-5)
• EPA Substance Registry System: Benzenecarbothioamide, N-[(dimethylamino)methylene]- (9CI)(52421-65-5)

Safety Data

• Hazardous Substances Data: 52421-65-5(Hazardous Substances Data)

Upstream product

• 41876-75-9 N¹,N¹-dimethyl-N²-benzoylformamidine 
• 2227-79-4 benzenecarbothioamide 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 52421-55-3 2-phenyl-1,3-thiazin-6-one 
• 72856-35-0 1-(2-phenyl-6H-1,3-thiazin-5-yl)-ethanone 
• 72856-32-7 4-dimethylamino-2-phenyl-5,6-dihydro-4H-[1,3]thiazine-5-carbonitrile 
• 72856-34-9 5-formyl-2-phenyl-6H-1,3-thiazine 
• 127956-56-3 4,5-dihydro-N,N-dimethyl-2-phenyl-1,3-thiazol-4-amine 
• 138371-12-7 bromure de 2-dimethylaminovinyltriphenylphosphonium 
• 138371-14-9 bromure de 2-(thiobenzamido)vinyltriphenylphosphonium 
• 138371-15-0 N-thiobenzoyliminoethylidenetriphenylphosphorane 
• 758-16-7 N,N-dimethylthioformamide 
• 100-47-0 benzonitrile 
• 72856-29-2 4,5-dihydro-6H-1,3-thiazine 
• 154917-89-2 4-dimethylamino-2-phenyl-6-tributylstannyl-4H-1,3-thiazine-5-methylcarboxylate 
• 52421-59-7 2-phenyl-1,3-thiazine-6-thione 
• 143361-15-3 5-aza-3-methoxycarbonyl-6-phenyl-6-thioxo-hex-3-enoate de methyle 

Relevant articles and documents

Convenient synthesis of 2,3-dihydro-1,2,4-thiadiazoles, 4,5-dihydro-1,3-thiazoles, and 1,3-thiazoles through a [4+1]-type oxidative ring closure of 1,3-thiaza-1,3-butadienes

1,3-Thiaza-1,3-butadienes bearing an N,N-dimethylamino group at the C-2 position were efficiently converted into 5H-1,2,4-oxathiazoles, 2,3-dihydro-1,2,4-thiadiazoles, 4,5-dihydro-1,3-thiazoles, and 1,3-thiazoles through an oxidative ring closure by treating with mCPBA, chloramine-T, metal carbenoids, or dichlorocarbene, respectively, via the ring closure of in situ generated heterocumulene-type reactive species involving thione S-oxides, thione S-imides, and thiocarbonyl ylides.

Thermolysis of Polyazapentadienes. Part 11. Concerted and Free Radical Mechanisms in 2-Aza Enone and 2-Aza Enthione Pyrolyses: Crystal and Molecular Structures of 3-Dimethylamino-1-p-tolyl-2-azaprop-2-en-1-one and 3-Dimethylamino-1-phenyl-2-azaprop-2-ene-1-thione

Flash vacuum pyrolysis of the dimethylamino-azapropenones (7)-(9) and -azapropenethione (12) gives nitriles and amides (or thioamide) in yields of ca. 30percent by an electrocyclisation-ring cleavage mechanism.This is a minor pathway for the triarylazapropenones (14) and (15) for which homolytic cleavage of the C-N bond gives rise to the major products.The X-ray crystal structures of (10) and (12) show that the conjugated systems are almost planar in the s-Z conformation, as required for the electrocyclic ring closure.

New Synthesis of 1,2,4-Thiadiazoles

A new synthesis of 1,2,4-thiadiazoles has been developed.N'-(Thioaroyl)- (and N'-arylthiocarbamoyl-) N,N-dimethylamidines, which were prepared in excellent yields by reactions of thioamides (and thioureas) with N,N-dimethylalkanamide dimethyl acetals, rea