52467-54-6 Usage
General Description
Z-Leu-Chloromethylketone, also known as Z-LCMK, is a synthetic chemical compound often used in scientific research as an inhibitor for serine proteases, which are enzymes that break down proteins and peptides. Its full name is Benzyloxycarbonyl-L-leucyl chloromethyl ketone. As a protease inhibitor, Z-Leu-Chloromethylketone has a significant value in biomedical research, particularly in understanding cellular processes and developing pharmaceuticals. Safety measures should be in place while handling this chemical as it may cause skin and eye irritation or harm if ingested or inhaled.
Check Digit Verification of cas no
The CAS Registry Mumber 52467-54-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,6 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 52467-54:
(7*5)+(6*2)+(5*4)+(4*6)+(3*7)+(2*5)+(1*4)=126
126 % 10 = 6
So 52467-54-6 is a valid CAS Registry Number.
52467-54-6Relevant articles and documents
Stereocontrolled synthesis of erythro N-protected α-amino epoxides and peptidyl epoxides
Albeck, Amnon,Persky, Rachel
, p. 6333 - 6346 (2007/10/02)
N-protected α-amino epoxides of erythro configuration, derived from α-amino acids, were synthesized in a stereoselective manner. The erythro (2S,3S), configuration was achieved by the synthetic sequence: amino acid -> haloketone -> halohydrin -> epoxide. A mechanistic explanation for the observed stereoselectivity is presented. This stereoselective synthetic approach was applied to the synthesis of a variety of short peptidyl epoxides, bearing a predefined absolute configuration of the chiral epoxide moiety.
