52479-85-3 Usage
Description
3,4,5,2',3',4'-Hexahydroxybenzophenone is a naturally occurring compound with a unique chemical structure characterized by six hydroxyl groups attached to a benzophenone core. It is known for its potent antioxidant, anti-inflammatory, and free radical scavenging properties, making it a valuable compound for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
3,4,5,2',3',4'-Hexahydroxybenzophenone is used as a therapeutic agent for its antioxidant, anti-inflammatory, and free radical scavenging properties. It can be employed in the development of drugs targeting various diseases, including neurodegenerative disorders, cardiovascular diseases, and cancer, due to its ability to protect cells from oxidative stress and inflammation.
Used in Cosmetic Industry:
3,4,5,2',3',4'-Hexahydroxybenzophenone is used as an active ingredient in cosmetic products for its antioxidant and anti-aging properties. It can help protect the skin from environmental stressors, such as UV radiation and pollution, and promote skin health by reducing the visible signs of aging, such as fine lines and wrinkles.
Used in Food Industry:
3,4,5,2',3',4'-Hexahydroxybenzophenone is used as a natural preservative and antioxidant in the food industry. It can help extend the shelf life of perishable products by neutralizing free radicals and preventing lipid oxidation, which can lead to rancidity and spoilage.
Used in Agricultural Industry:
3,4,5,2',3',4'-Hexahydroxybenzophenone can be used as a natural pesticide or fungicide in the agricultural industry. Its antioxidant and anti-inflammatory properties can help protect crops from various diseases and pests, promoting healthy plant growth and increased crop yields.
Used in Environmental Applications:
3,4,5,2',3',4'-Hexahydroxybenzophenone can be utilized in environmental applications, such as water and air purification, due to its ability to neutralize harmful pollutants and toxins. It can be employed in the development of eco-friendly technologies for the remediation of contaminated sites and the reduction of environmental pollution.
Originator
Pharmascience (France)
Preparation
Preparation by condensation of gallic acid with pyrogallol, ? in the presence of zinc chloride at 120° (good yield) or at 145° for 3 h (Nencki reaction); ? in the presence of zinc chloride and phosphorous oxychloride at 80° for 2 h, via Fries rearrangement.
Check Digit Verification of cas no
The CAS Registry Mumber 52479-85-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,4,7 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 52479-85:
(7*5)+(6*2)+(5*4)+(4*7)+(3*9)+(2*8)+(1*5)=143
143 % 10 = 3
So 52479-85-3 is a valid CAS Registry Number.
52479-85-3Relevant articles and documents
Evaluation of polyhydroxybenzophenones as α-glucosidase inhibitors
Hu, Xuesen,Xiao, Yang,Wu, Jianlong,Ma, Lin
experimental part, p. 71 - 77 (2011/09/21)
This experiment was designed to synthesize 18 kinds of polyhydroxybenzophenones by using Friedel-Crafts reaction, and to measure the inhibitory activity on α-glucosidase with p-nitrophenyl-β-D- galactopyranoside (PNPG) as a substrate. Here, acarbose (IC50a= a1674.75aaμmolaL-1) was used as the reference inhibitor. The results demonstrated that most of the target compounds had remarkable inhibitory activities on α-glucosidase. Among all these compounds, 2,4,4′,6-butahydroxydiphenylketone (11) was found to be the most potent α-glucosidase inhibitor with an IC50 value of 10.62aaμmolaL-1. In addition, we found these compounds were competitive inhibitors through the kinetic analysis. The results suggested that such compounds might be utilized for the development of new candidates for diabetes treatment. A series of polyhydroxybenzophenones was synthesized and evaluated as α-glucosidase inhibitors. Compound 11 was found to be the most potent inhibitor. Copyright
