52480-31-6

Basic information

• Product Name: 3-Pyridinesulfonamide, 6-chloro-N,N-dimethyl-
• Synonyms: 2-chloro-5-(N,N-dimethylaminosulfonyl)pyridine;6-chloro-pyridine-3-sulfonic acid dimethylamide;6-Chlor-pyridin-3-sulfonsaeure-dimethylamid;2-chloro-5-N,N-dimethylsulfonamidopyridine
• CAS NO: 52480-31-6
• Molecular Formula: C7H9ClN2O2S
• Molecular Weight: 220.67700
• Mol File: 52480-31-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 339.0±52.0 °C(Predicted)
• Density: 1.377±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 3-Pyridinesulfonamide, 6-chloro-N,N-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinesulfonamide, 6-chloro-N,N-dimethyl-(52480-31-6)
• EPA Substance Registry System: 3-Pyridinesulfonamide, 6-chloro-N,N-dimethyl-(52480-31-6)

Safety Data

• Hazardous Substances Data: 52480-31-6(Hazardous Substances Data)

Upstream product

• 6684-39-5 2-chloropyridine-5-sulfonyl chloride 
• 124-40-3 dimethyl amine 

Downstream Products

• 627836-23-1 6-amino-N,N-dimethylpyridine-3-sulfonamide 

Relevant articles and documents

Novel sulfone amide derivatives compound, Manufacturing method thereof, Phamaceutical composition for preventing and treating cancer containing the same, and Methods for preventing and treating cancer using the same

The present invention relates to novel sulfonamide-based derivatives, a manufacturing method thereof, and to a pharmaceutical composition comprising the same for preventing or treating cancer. More particularly, the novel sulfonamide-based derivatives target Rab27a, and hinder or suppress expression of the Rab27a. Also, the present invention relates to a method for preventing or treating cancer using the pharmaceutical composition.

PYRROLOPYRIMIDINE COMPOUNDS AND USES THEREOF

The present disclosure provides pyrrolopyrimidine compounds and methods of use therefor. For example, the disclosure provides certain pyrrolopyrimidine compounds capable of inhibiting JAK kinases. The disclosure further provides the pharmaceutical compositions containing these pyrrolopyrimidine compounds, and use of these pyrrolopyrimidine compounds in the treatment of disorders or diseases, such as inflammatory diseases and cancer.

PYRROLOPYRIMIDINE COMPOUNDS AND USES THEREOF

The present invention provides pyrrolopyrimidine compounds and methods of use therefor. In particular, the invention provides certain pyrrolopyrimidine compounds having the activity of inhibiting JAK kinases. The invention also provides the pharmaceutical compositions containing these pyrrolopyrimidine compounds and use of these compounds in the treatment of inflammatory diseases and cancer.