5263-58-1

Basic information

• Product Name: Benzeneethanamine, N-2-propenyl-
• CAS NO: 5263-58-1
• Molecular Formula: C11H15N
• Molecular Weight: 161.247
• Mol File: 5263-58-1.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzeneethanamine, N-2-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanamine, N-2-propenyl-(5263-58-1)
• EPA Substance Registry System: Benzeneethanamine, N-2-propenyl-(5263-58-1)

Safety Data

• Hazardous Substances Data: 5263-58-1(Hazardous Substances Data)

Upstream product

• 6125-24-2 2-Phenylnitroethane 
• 591-87-7 Allyl acetate 
• 64-04-0 phenethylamine 
• 107-11-9 1-amino-2-propene 
• 106-95-6 allyl bromide 
• 6728-21-8 allyl mesylate 
• 105824-25-7 C₁₁H₁₃N 
• 70867-37-7 1-(allyloxycarbonyl)phenethylamine 
• 74974-19-9 benzylmethyleneimine 
• 10017-11-5 allylammonium chloride 
• 4383-22-6 Allylbenzylamine 
• 23696-40-4 trimethylstannylmethyl iodide 
• 103-63-9 1-phenyl-2-bromoethane 

Downstream Products

• 55246-59-8 C₁₂H₁₄ClNO 
• 1276126-38-5 C₁₈H₂₃NO₃ 
• 1276126-48-7 C₁₆H₁₉NO₃ 
• 798542-77-5 N-hydroxy-3-(2-oxo-1-phenethyl-2,5-dihydro-1H-pyrrol-3-yl)-propionamide 
• 61357-18-4 N-allyl-N-phenethylacetamide 

Relevant articles and documents

Direct Reductive N-Functionalization of Aliphatic Nitro Compounds

The first general protocol for the direct reductive N-functionalization of aliphatic nitro compounds is presented. The nitro group is partially reduced to a nitrenoid, with a mild and readily available combination of B2pin2 and zinc organyls. Thereby, the formation of an unstable nitroso intermediate is avoided, which has so far severely limited reductive transformations of aliphatic nitro compounds. The reaction is concluded by an electrophilic amination of zinc organyls.

Sequence-defined polymers via orthogonal allyl acrylamide building blocks

Biological systems have long recognized the importance of macromolecular diversity and have evolved efficient processes for the rapid synthesis of sequence-defined biopolymers. However, achieving sequence control via synthetic methods has proven to be a difficult challenge. Herein we describe efforts to circumvent this difficulty via the use of orthogonal allyl acrylamide building blocks and a liquid-phase fluorous support for the de novo design and synthesis of sequence-specific polymers. We demonstrate proof-of-concept via synthesis and characterization of two sequence-isomeric 10-mer polymers. 1H NMR and LCMS were used to confirm their chemical structure while tandem MS was used to confirm sequence identity. Further validation of this methodology was provided via the successful synthesis of a sequence-specific 16-mer polymer incorporating nine different monomers. This strategy thus shows promise as an efficient approach for the assembly of sequence-specific functional polymers.

PRODUCTION METHOD FOR 2-ALKENYLAMINE COMPOUND

Provided is a method for producing a 2-alkenylamine compound efficiently and at low cost, using a primary or secondary amine compound and a 2-alkenyl compound as the starting materials therefor. The 2-alkenylamine compound is produced by adding Bronsted acid when 2-alkenylating by reacting the primary or secondary amine compound with the 2-alkenyl compound, and 2-alkenylating in the presence of a catalyst comprising a complexing agent and a transition metal precursor stabilized by a monovalent anionic five-membered conjugated diene.