5264-17-5

Basic information

• Product Name: 4-(4-CHLOROBUTYL) PYRIDINE
• Synonyms: 4-(4-CHLOROBUTYL) PYRIDINE;Pyridine, 4-(4-chlorobutyl)-
• CAS NO: 5264-17-5
• Molecular Formula: C₉H₁₂ClN
• Molecular Weight: 169.65
• Mol File: 5264-17-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 277℃
• Flash Point: 148℃
• Appearance: /
• Density: 1.061
• Storage Temp.: 2-8°C
• PKA: 6.04±0.10(Predicted)
• CAS DataBase Reference: 4-(4-CHLOROBUTYL) PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-CHLOROBUTYL) PYRIDINE(5264-17-5)
• EPA Substance Registry System: 4-(4-CHLOROBUTYL) PYRIDINE(5264-17-5)

Safety Data

• Hazardous Substances Data: 5264-17-5(Hazardous Substances Data)

Usage

General Description

4-(4-chlorobutyl)pyridine is a chemical compound with the molecular formula C9H12ClN. It is a colorless to light yellow liquid with a boiling point of 217-218°C. 4-(4-CHLOROBUTYL) PYRIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is known to have a strong, unpleasant odor and should be handled with care due to its potential irritant properties. Additionally, 4-(4-chlorobutyl)pyridine is used in the manufacturing of corrosion inhibitors and in the production of specialty chemicals. It is important to follow proper safety precautions when working with this compound to minimize any potential health or environmental hazards.

Upstream product

• 108-89-4 picoline 
• 109-70-6 1.3-chlorobromopropane 
• 100-43-6 4-vinylpyridine 
• 102878-73-9 γ-(pyridin-4-yl)butyric acid 
• 10297-05-9 1-chloro 4-iodobutane 
• 5264-15-3 4-(4-pyridinyl)butan-1-ol 

Downstream Products

• 149490-61-9 N-(n-butanesulfonyl)-O-(4-(4-pyridinyl)-butyl)-(S)-tyrosine 
• 144494-65-5 tirofiban hydrochloride 
• 144494-65-5 tirofiban 
• 37778-33-9 ethyl 8-azaspiro[4.5]deca-6,9-diene-8-carboxylate 
• 148341-95-1 hexahydro-7-(4-methoxyphenyl)-4-[4-(4-pyridinyl)butyl]-1,4-thiazepine 

Relevant articles and documents

Synthesis method of tirofiban hydrochloride intermediate III (by machine translation)

The invention belongs to the field, of medicine synthesis, and particularly relates to a synthesis method III of tirofiban hydrochloride intermediate. by, reduction of an intermediate I under the action of a sodium borohydride reducing system to obtain intermediate II, intermediate II under Lewis acid chloride in the presence. SOCl2 Reaction conditions of, process are mild III, and N - process operation is simple, the reaction conditions of the reaction yield, product are improved, the product purity is high, and the reaction yield is increased by, times without being subjected to column purification, to improve the clinical medication safety, of the injection using, the standard crude drug product of the pharmacopoeia standard, and is suitable, for industrial production. (by machine translation)

Nickel-catalyzed cross-coupling of potassium aryl- and heteroaryltrifluoroborates with unactivated alkyl halides

A method for the cross-coupling of alkyl electrophiles with various potassium aryl- and heteroaryltrifluoroborates has been developed. Nearly stoichiometric amounts of organoboron species could be employed to cross-couple a large variety of challenging heteroaryl nucleophiles. Several functional groups were tolerated on both the electrophilic and the nucleophilic partners. Chemoselective reactivity of C(sp3) - Br bonds in the presence of C(sp2) - Br bonds was achieved.

Synthesis of RGD analogs as potential vectors for targeted drug delivery

RGD analogs bind to integrin receptors with high affinity and therefore have the potential to be used as vectors for the targeted delivery of pharmaceutical agents to designated sites. Critical to this application is the ability to synthesize RGD analogs