52660-18-1

Basic information

• Product Name: CASEIN KINASE II
• Synonyms: ANTI-MOUSE CSNK2A2 (N-TERM) antibody produced in rabbit;Csnk2a2;Anti-Casein Kinase II α antibody produced in rabbit;CK2-α1;CKIIA;CSK21;Anti-CKII-β, C-Terminal antibody produced in rabbit;CK2N
• CAS NO: 52660-18-1
• Molecular Formula: C90H153N27O26
• Molecular Weight: 2029.34
• Mol File: 52660-18-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /buffered aqueous glycerol solution
• Storage Temp.: −20°C
• CAS DataBase Reference: CASEIN KINASE II(CAS DataBase Reference)
• NIST Chemistry Reference: CASEIN KINASE II(52660-18-1)
• EPA Substance Registry System: CASEIN KINASE II(52660-18-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• WGK Germany: 1
• Hazardous Substances Data: 52660-18-1(Hazardous Substances Data)

Usage

Description

Casein Kinase II (CK2) is a serine/threonine protein kinase that plays a crucial role in the regulation of several cellular processes, including cell growth, proliferation, and survival. It is a constitutively active enzyme that phosphorylates a wide range of substrates, including transcription factors, RNA polymerase, and several other kinases, thereby modulating their activity. CK2 has been implicated in various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions, making it a potential therapeutic target. Its dysregulation has been linked to aberrant cell signaling and uncontrolled cellular proliferation, highlighting the importance of studying and understanding its function in health and disease.

Uses

Used in Pharmaceutical Industry:
CK2 is used as a therapeutic target for the development of drugs to treat various diseases, such as cancer, neurodegenerative disorders, and inflammatory conditions. Its dysregulation has been linked to aberrant cell signaling and uncontrolled cellular proliferation, making it an important target for drug discovery and development.
Used in Research and Development:
CK2 is used as a research tool to study the regulation of cellular processes, such as cell growth, proliferation, and survival. Understanding its function in health and disease can provide valuable insights into the development of new therapeutic strategies and interventions.
Used in Diagnostics:
CK2 can be used as a biomarker for the diagnosis and monitoring of diseases, such as cancer, neurodegenerative disorders, and inflammatory conditions. Its dysregulation can serve as an indicator of disease progression and response to treatment, aiding in the development of personalized medicine approaches.