527-09-3 Usage
Description
D-Gluconic acid copper(II) salt, also known as Copper(II) gluconate, is the copper salt of D-gluconic acid, an organic acid. It is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol. Copper is an essential microelement for human beings and animals, playing a vital role in various biochemical reactions and being a key component of multiple enzymes.
Uses
Used in Skin Care Industry:
D-Gluconic acid copper(II) salt is used as a skin-conditioning and skin-protecting agent for its beneficial effects on the skin.
Used in Dietary Supplements:
D-Gluconic acid copper(II) salt is used as a copper supplement in dietary supplements, helping to treat copper deficiency-induced anemia and nephrosis.
Used in Pharmaceutical Industry:
D-Gluconic acid copper(II) salt is used to treat various health conditions such as acne vulgaris, common cold, hypertension, premature labor, leishmaniasis, and visceral postoperative complications.
Used in Oral Care Industry:
D-Gluconic acid copper(II) salt is used in oral deodorants for its beneficial properties.
Used in Animal Feed Industry:
D-Gluconic acid copper(II) salt is used as an additive in the animal feed industry to support the health and well-being of animals.
Used in Food Industry:
D-Gluconic acid copper(II) salt is used as a synergist and nutritional supplement for the food industry, particularly as the active component in retsyn used in mints and certs.
Used in Cancer Chemotherapy:
D-Gluconic acid copper(II) salt is used in cancer chemotherapy, as it is capable of enhancing the efficacy of the anticancer drug, disulfiram.
Used in Drug Delivery Systems:
D-Gluconic acid copper(II) salt can be used as a buffer for encapsulating some drugs into liposomes, improving their delivery and effectiveness.
References
Dicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.
Preparation
Copper(II) gluconate is prepared by the dissolution of copper(II) carbonate or copper(II) hydroxide in gluconic acid. It is used as a nutritional supplement for copper deficiency and as a component in oral deodorants.
Flammability and Explosibility
Notclassified
Safety Profile
When heated to
decomposition it emits acrid smoke and
irritating fumes.
Check Digit Verification of cas no
The CAS Registry Mumber 527-09-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 527-09:
(5*5)+(4*2)+(3*7)+(2*0)+(1*9)=63
63 % 10 = 3
So 527-09-3 is a valid CAS Registry Number.
InChI:InChI=1/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1/rC12H22CuO14/c14-1-3(16)5(18)7(20)9(22)11(24)26-13-27-12(25)10(23)8(21)6(19)4(17)2-15/h3-10,14-23H,1-2H2/t3-,4-,5-,6-,7+,8+,9-,10-/m1/s1
