52709-42-9Relevant articles and documents
Simple Syntheses of Diethyl Oxomalonate and Alkyl Glyoxylates
Jung, Michael E.,Shishido, Kozo,Davis, Leonard H.
, p. 891 - 892 (1982)
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Asymmetric Catalytic Aza-Diels–Alder/Ring-Closing Cascade Reaction Forming Bicyclic Azaheterocycles by Trienamine Catalysis
Li, Yang,Barl?se, Casper,J?rgensen, Julie,Carlsen, Bj?rn Drei?,J?rgensen, Karl Anker
supporting information, p. 38 - 41 (2017/01/09)
An asymmetric catalytic aza-Diels–Alder/ring-closing cascade reaction between acylhydrazones and in situ formed trienamines is presented. The reaction proceeds through a formal aza-Diels–Alder cycloaddition, followed by a ring-closing reaction forming the hemiaminal ring leading to chiral bicyclic azaheterocycles in moderate to good yield (up to 71 %), good enantio- (up to 92 % ee) and diastereoselectivity (up to >20:1 d.r.). Furthermore, transformations are presented to show the potential application of the formed product.
The catalytic synthesis of carboniolamide: The role of sp 3 hybridized oxygen
Zhang, Yi,Dai, Yuchi,Li, Guigen,Cheng, Xu
, p. 2644 - 2648 (2015/02/02)
A catalytic synthesis of carboniolamide has been reported. The strategy was straightforward with aldehyde and amide as starting materials. The products can be isolated as precipitates from the reaction mixture. The factor that stabilizes the labile functionality of hemiaminal was elucidated as a sp 3 hybridized oxygen.
