5271-26-1 Usage
Description
2-Phenylpiperazine is an organic compound with the molecular formula C10H14N2. It is a heterocyclic compound featuring a piperazine ring with a phenyl group attached to the second carbon. This structure grants it unique chemical and biological properties, making it a versatile building block in the synthesis of various pharmaceutical and chemical compounds.
Uses
Used in Pharmaceutical Industry:
2-Phenylpiperazine is used as a starting material for the synthesis of various 2-phenylpiperazine compounds, which have a wide range of applications in the pharmaceutical industry. These synthesized compounds can exhibit diverse pharmacological activities, such as acting as antidepressants, anxiolytics, and antipsychotics. The structural flexibility of 2-phenylpiperazine allows for the development of new drugs with improved efficacy and reduced side effects.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-Phenylpiperazine serves as a key intermediate for the creation of a variety of complex organic molecules. Its unique structure allows for further functionalization and modification, leading to the development of new compounds with specific properties and applications in various industries, such as materials science, agrochemicals, and dyes.
Some specific examples of synthesized compounds from 2-Phenylpiperazine include:
1. 1,4-Dimethyl-2-phenylpiperazine: 2-Phenylpiperazine has been synthesized for its potential applications in the pharmaceutical industry, particularly as a precursor to drugs with central nervous system activity.
2. 1,4-Diethyl-2-phenylpiperazine: Similar to its dimethyl counterpart, this compound is also synthesized for its potential use in the development of pharmaceuticals, with a focus on compounds that target the central nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 5271-26-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,7 and 1 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5271-26:
(6*5)+(5*2)+(4*7)+(3*1)+(2*2)+(1*6)=81
81 % 10 = 1
So 5271-26-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2/c1-2-4-9(5-3-1)10-8-11-6-7-12-10/h1-5,10-12H,6-8H2
5271-26-1Relevant articles and documents
A simple one-pot method for the mercuric oxide mediated synthesis of piperazines via oxidative diamination of olefins
Kour, Harpreet,Paul, Satya,Singh, Parvinder Pal,Gupta, Monika,Gupta, Rajive
, p. 761 - 764 (2013/02/25)
Mercuric oxide mediated one-pot synthesis of substituted piperazines via oxidative diamination of olefins with N-protected ethylene diamine has been reported. Among the various conditions tried, mercuric(II)oxide/tetrafluoroboric acid gave good to excellent yields of the desired products. A series of piperazines have been synthesized and characterized by NMR and mass spectroscopy methods.
COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USES AS IDH1 MUTANTS INHIBITORS FOR TREATING CANCERS
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Page/Page column 115, (2013/02/28)
Provided are compounds of formula (I), wherein X, Y, Z, W, V, R2, R3 and m are defined as in the description. Their pharmaceutical compositions and their uses as IDH1 mutants inhibitors for treating cancers are also provided
AMIDO-THIOPHENE COMPOUNDS AND THEIR USE
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Page/Page column 140-141, (2009/10/22)
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain amido-thiophene compounds that, inter alia, inhibit 11 β-hydroxysteroid dehydrogenase type 1 (11 β-HSD1 ). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit 11 β-hydroxysteroid dehydrogenase type 1; to treat disorders that are ameliorated by the inhibition of 11 β-hydroxysteroid dehydrogenase type 1; to treat the metabolic syndrome, which includes disorders such as type 2 diabetes and obesity, and associated disorders including insulin resistance, hypertension, lipid disorders and cardiovascular disorders such as ischaemic (coronary) heart disease; to treat CNS disorders such as mild cognitive impairment and early dementia, including Alzheimer's disease; etc.