527755-11-9

Basic information

• Product Name: Cyclohexanone, 2-[(1E)-1,5-dimethyl-1-hexenyl]-5-ethyl-4-hydroxy-3-methoxy-, (2S,3S,4R,5R)-
• CAS NO: 527755-11-9
• Molecular Formula: C17H30O3
• Molecular Weight: 282.423
• Mol File: 527755-11-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2-[(1E)-1,5-dimethyl-1-hexenyl]-5-ethyl-4-hydroxy-3-methoxy-, (2S,3S,4R,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2-[(1E)-1,5-dimethyl-1-hexenyl]-5-ethyl-4-hydroxy-3-methoxy-, (2S,3S,4R,5R)-(527755-11-9)
• EPA Substance Registry System: Cyclohexanone, 2-[(1E)-1,5-dimethyl-1-hexenyl]-5-ethyl-4-hydroxy-3-methoxy-, (2S,3S,4R,5R)-(527755-11-9)

Safety Data

• Hazardous Substances Data: 527755-11-9(Hazardous Substances Data)

Upstream product

• 56134-54-4 (E)-3,7-dimethyloct-3-enol 
• 527755-03-9 (4R,5S,6S)-6-[(E)-1,5-dimethylhex-1-enyl]-4-hydroxy-5-methoxycyclohex-2-enone 
• 97-93-8 triethylaluminum 
• 527754-88-7 (4R)-4-benzyl-3-[(2S)-2-[(1S,2R)-1-hydroxy-2-p-methoxybenzyloxybut-3-enyl]-3,7-dimethylocta-3-enoyl]oxazolidin-2-one 
• 527754-90-1 (2S)-2-[(1S,2R)-1-hydroxy-2-p-methoxybenzyloxybut-3-enyl]-3,7-dimethylocta-3-enoic acid methoxymethylamide 
• 527754-92-3 (2S)-2-[(1S,2R)-1-methoxy-2-p-methoxybenzyloxybut-3-enyl]-3,7-dimethylocta-3-enoic acid methoxymethylamide 
• 527754-94-5 (4S)-4-((1S,2R)-1-methoxy-2-p-methoxybenzyloxybut-3-enyl)-5,9-dimethyldeca-1,5-dien-3-one 
• 527754-96-7 (4R,5S,6S)-5-methoxy-4-p-methoxybenzyloxy-6-[(E)-1,5-dimethylhex-1-enyl]cyclohex-2-enone 
• 527754-86-5 (4R)-4-benzyl-3-[(3E)-3,7-dimethylocta-3-enoyl]oxazolidin-2-one 
• 527754-85-4 (3E)-3,7-dimethyloct-3-enoic acid 
• 78592-77-5 (E)-4-tert-butyldimethylsilyloxy-1-iodo-2-methyl-1-butene 
• 78592-73-1 (E)-4-iodo-3-methylbut-3-en-1-ol 

Downstream Products

• 655253-32-0 (3R,4S,5S,6R,7R)-6-benzoyloxy-4-[(1R,2R)-1,2-epoxy-1,5-dimethylhexyl]-7-ethyl-5-methoxy-1-oxaspiro[2.5]octane 
• 527755-15-3 (3R,4S,5S,6R,7R)-6-benzoyloxy-4-[(E)-1,5-dimethylhex-1-enyl]-5-methoxy-7-ethyl-1-oxaspiro[2.5]octane 
• 527755-13-1 (2S,3S,4R,5R)-4-benzoyloxy-5-ethyl-3-methoxy-2-[(E)-1,5-dimethylhex-1-enyl]cyclohexanone 

Relevant articles and documents

MetAP-2 Inhibitors Based on the Fumagillin Structure. Side-Chain Modification and Ring-Substituted Analogues

The preparation of a series of new fumagillin-derived MetAP-2 inhibitors is described. The synthetic approach was designed so as to permit modification of the fumagillin backbone at sites inaccessible through semisynthesis or previously existing total syntheses. An Evans aldolization and a ring-closing metathesis allowed the preparation of a pivotal intermediate which could then be functionalized in various ways using already established or newly developed methodologies.