5278-56-8

Basic information

• Product Name: 2-(o-nitrophenyl)quinoline
• Synonyms: 2-(o-nitrophenyl)quinoline
• CAS NO: 5278-56-8
• Molecular Weight: 250.257
• Mol File: 5278-56-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-(o-nitrophenyl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(o-nitrophenyl)quinoline(5278-56-8)
• EPA Substance Registry System: 2-(o-nitrophenyl)quinoline(5278-56-8)

Safety Data

• Hazardous Substances Data: 5278-56-8(Hazardous Substances Data)

Upstream product

• 1466-88-2 2-nitrocinnamic aldehyde 
• 62-53-3 aniline 
• 1466-88-2 2-nitrocinnamaldehyde 
• 7647-01-0 hydrogenchloride 
• 874212-39-2 (Z)-3-Chloro-3-(2-nitro-phenyl)-propenal 
• 577-59-3 2-acetylnitrobenzene 
• 612-96-4 2-Phenylquinoline 
• 552-89-6 2-nitro-benzaldehyde 
• 529-23-7 o-aminobenzaldehyde 
• 5570-19-4 2-nitrophenylboronic acid 

Downstream Products

• 117838-48-9 2-(2'-azidophenyl)quinoline 
• 480-26-2 cryptolepine 
• 29184-58-5 2-(2-aminophenyl)quinoline 

Relevant articles and documents

Visible-light-driven Cadogan reaction

Visible-light-driven photochemical Cadogan-type cyclization has been discovered. The organic D-A type photosensitizer 4CzIPN found to be an efficient mediator to transfer energy from photons to the transient intermediate that breaks the barriers of deoxygenation in Cadogan reaction and enables a mild metal-free access to carbazoles and related heterocycles. DFT calculation results indicate mildly endergonic formation of the intermediate complex of nitrobiarenes and PPh3, which corresponds with experimental findings regarding reaction temperature. The robust synthetic capacity of the photoredox Cadogan reaction systems has been demonstrated by the viable productivity of a broad range of carbazoles and related N-heterocycles with good tolerance of various functionalities.

Rhodium(III)-catalyzed azidation and nitration of arenes by C-H activation

Getting a handle on it: In the chelation-assisted title reactions in the presence of a hypervalent iodine oxidant, sodium azide and sodium nitrite served as readily available nitrogen sources, and pyridine, pyrimidine, and pyrazole substituents were effic

Synthesis of quinolines by a solid acid-catalyzed microwave-assisted domino cyclization-aromatization approach

A microwave-assisted solid acid-catalyzed synthesis of quinolines from anilines and cinnamaldehydes is described. Use of montmorillonite K-10 results in a one-pot process; the cyclization and oxidation steps readily take place in a domino approach. Reactions were completed in a matter of minutes and provided excellent yields. The efficient and ecofriendly catalyst and the convenience of the product isolation make this process an attractive alternative for the synthesis of these important heterocycles.