52780-23-1

Basic information

• Product Name: 5-chlorobenzene-1,3-diol
• Synonyms: 5-chlorobenzene-1,3-diol;1,3-Benzenediol, 5-chloro-;5-Chlororesorcinol;1-Chloro-3,5-dihydroxybenzene
• CAS NO: 52780-23-1
• Molecular Formula: C₆H₅ClO₂
• Molecular Weight: 144.56
• Mol File: 52780-23-1.mol
• Article Data: 16

Chemical Properties

• Melting Point: 119℃
• Boiling Point: 196.14°C (rough estimate)
• Flash Point: 119.9°C
• Appearance: /
• Density: 1.2558 (rough estimate)
• Vapor Pressure: 0.00319mmHg at 25°C
• Refractive Index: 1.4620 (estimate)
• PKA: 8.49±0.10(Predicted)
• CAS DataBase Reference: 5-chlorobenzene-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chlorobenzene-1,3-diol(52780-23-1)
• EPA Substance Registry System: 5-chlorobenzene-1,3-diol(52780-23-1)

Safety Data

• Hazardous Substances Data: 52780-23-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H5ClO2/c7-4-1-5(8)3-6(9)2-4/h1-3,8-9H

Upstream product

• 65262-96-6 3-chloro-5-methoxyphenol 
• 50375-08-1 1,3-diethoxy-5-chloro-benzene 
• 98273-26-8 2,3,4-trichloro-5-methoxy-phenol 
• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 10272-06-7 3-chloro-5-methoxyaniline 
• 98555-81-8 2,3,4,4-tetrachloro-5-methoxy-cyclohexa-2,5-dienone 
• 108-70-3 1,3,5-trichlorobenzene 

Downstream Products

• 101676-68-0 3,5-dinitro-benzoic acid-(3-chloro-5-hydroxy-phenyl ester) 
• 162155-68-2 2-chloro-benzenesulfonic acid 3-chloro-5-hydroxy-phenyl ester 
• 87006-36-8 4-chloro-2,6-dihydroxybenzoic acid 
• 257621-56-0 4'-chloro-2',6'-dihydroxyacetophenone 
• 257621-36-6 4'-chloro-2',6'-dihydroxyacetophenone 2'-O-(2,3,4,6-O-tetraacetyl)-β-D-glucopyranoside 
• 436864-83-4 methyl 4-chloro-2,6-dihydroxybenzoate 
• 1027265-14-0 1-(3-acetyl-6-chloro-2,4-dihydroxy-phenyl)-ethanone 
• 163301-14-2 1,3-bis(4-formylphenoxy)-5-chlorobenzene 
• 1242610-32-7 C₅₈H₆₉ClO₁₀ 
• 1242610-34-9 C₆₆H₈₅ClO₁₀ 

Relevant articles and documents

Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence

Anti-virulence approaches in the treatment of Pseudomonas aeruginosa (PA)-induced infections have shown clinical potential in multiple in vitro and in vivo studies. However, development of these compounds is limited by several factors, including the lack of molecules capable of penetrating the membrane of gram-negative organisms. Here, we report the identification of novel structurally diverse compounds that inhibit PqsR and LasR-based signaling and diminish virulence factor production and biofilm growth in two clinically relevant strains of P. aeruginosa. It is the first report where potential anti-virulent agents were evaluated for inhibition of several virulence factors of PA. Finally, co-treatment with these inhibitors significantly reduced the production of virulence factors induced by the presence of sub-inhibitory levels of ciprofloxacin. Further, we have analyzed the drug-likeness profile of designed compounds using quantitative estimates of drug-likeness (QED) and confirmed their potential as hit molecules for further development.

COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

Disclosed are a compound for an organic optoelectronic device, a composition for an organic optoelectronic device including the same, an organic optoelectronic device including the composition for an organic optoelectronic device as a host, and a display

COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE

The present invention relates to a compound represented by a combination of chemical formula 1 and chemical formula 2, a composition including the compound, an organic optoelectronic device, and a display device. In the chemical formula 1 and chemical for