5279-58-3

Basic information

• Product Name: Formamide, N-[4-(1-methylethyl)phenyl]- (9CI)
• Synonyms: Formamide, N-[4-(1-methylethyl)phenyl]- (9CI)
• CAS NO: 5279-58-3
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.21632
• Product Categories: ISOPROPYL
• Mol File: 5279-58-3.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Formamide, N-[4-(1-methylethyl)phenyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Formamide, N-[4-(1-methylethyl)phenyl]- (9CI)(5279-58-3)
• EPA Substance Registry System: Formamide, N-[4-(1-methylethyl)phenyl]- (9CI)(5279-58-3)

Safety Data

• Hazardous Substances Data: 5279-58-3(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 99-88-7 4-Isopropylaniline 
• 124-38-9 carbon dioxide 
• 68-12-2 N,N-dimethyl-formamide 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 

Downstream Products

• 1474041-93-4 1-(2-cyclohex-1-enylethyl)-3-(4-isopropylphenyl)selenourea 
• 1474042-02-8 4-isopropylphenyl(1-selena-3-azaspiro[5.5]undec-2-en-2-yl)amine hydrobromide 
• 5279-57-2 N-(4-isopropylphenyl)-N-methylformamide 
• 463302-31-0 para-isopropylphenyl isocyanide 
• 5892-70-6 4-isopropylaniline hydrochloride 
• 99-88-7 4-Isopropylaniline 
• 86781-17-1 1,1-dibutyl-3-(4-isopropylphenyl)urea 
• 31027-31-3 4-isopropylphenylisocyanate 
• 459412-95-4 butyl (4-isopropylphenyl)carbamate 
• 1028862-11-4 C₁₀H₁₁NSe 

Relevant articles and documents

Facile N-Formylation of Amines on Magnetic Fe3O4?CuO Nanocomposites

A facile, eco-friendly, efficient, and recyclable heterogeneous catalyst is synthesized by immobilizing copper impregnated on mesoporous magnetic nanoparticles. The surface chemistry analysis of Fe3O4?CuO nanocomposites (NCs) by XRD and XPS demonstrates the synergistic effect between Fe3O4 and CuO nanoparticles, providing mass-transfer channels for the catalytic reaction. TEM images clearly indicate the impregnation of CuO onto mesoporous Fe3O4. This hydrothermally synthesized eco-friendly and highly efficient Fe3O4?CuO NCs are applied as a magnetically retrievable heterogeneous catalyst for the N-formylation of wide range of aliphatic, aromatic, polyaromatic and heteroaromatic amines using formic acid as a formylating agent at room temperature. The catalytic activity of the NCs for N-formylation is attributable to the synergistic effect between Fe3O4 and CuO nanoparticles. The N-formylated product is further employed for the synthesis of biologically active quinolone moieties.

Method of N-formylating amines with a phosphonic anhydride

A method for N-formylating an amine that includes reacting the amine and a formamide compound in the presence of a phosphonic anhydride to form an N-formylated amine. The phosphonic anhydride is present in an amount of 5-100 mol % relative to a total number of moles of the amine, and the reacting is performed for 1-24 hours at a temperature of 45-100° C.

A process for preparing N - aryl amide compound

The method discloses a method used for preparing an N-aryl amide compound from amides and aniline compounds. According to the method, a palladium salt and a ligand are taken as catalysts; an N,N-dimethyl formamide compound, an aniline compound, a protonic acid, a Lewis acid, and an organic solvent are mixed; and an obtained mixture is subjected to heating reaction so as to obtain the N-aryl amide compound. Advantages of the method are that: preparation route is short, substrate universality is excellent, reaction conditions are mild, synthesis yield is high, and used raw materials and catalysts are simple and easily available.