52813-48-6

Basic information

• Product Name: 3-Bromo-2,2-bis(bromomethyl)propanoicacid
• Synonyms: 3-Bromo-2,2-bis(bromomethyl)propanoicacid;2,2-BIS(BROMOMETHYL)-3-BROMOPROPANOIC ACID
• CAS NO: 52813-48-6
• Molecular Formula: C₅H₇Br₃O₂
• Molecular Weight: 338.81988
• Mol File: 52813-48-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Bromo-2,2-bis(bromomethyl)propanoicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-2,2-bis(bromomethyl)propanoicacid(52813-48-6)
• EPA Substance Registry System: 3-Bromo-2,2-bis(bromomethyl)propanoicacid(52813-48-6)

Safety Data

• Hazardous Substances Data: 52813-48-6(Hazardous Substances Data)

Upstream product

• 3296-90-0 bis(bromomethyl)bis(hydroxymethyl)methane 
• 1522-92-5 2,2-bis(bromomethyl)-3-bromo-propan-1-ol 

Downstream Products

• 1431967-53-1 3-(tritylthio)-2,2-bis((tritylthio)methyl)propanoic acid 
• 15378-31-1 3-bromo-2-(bromomethyl)-1-propene 
• 3775-29-9 1,3-diacetoxy-2-methylenepropane 
• 2831-90-5 α,α,α-tris(hydroxymethyl)acetic acid 
• 99859-58-2 3-bromo-2,2-bis-bromomethyl-propionic acid anilide 
• 100119-06-0 3-bromo-2,2-bis-bromomethyl-1-p-tolyl-propan-1-one 
• 99853-46-0 3-bromo-2,2-bis-bromomethyl-1-phenyl-propan-1-one 

Relevant articles and documents

Development of safe, scalable nitric acid oxidation using a catalytic amount of NaNO2 for 3-bromo-2,2-bis(bromomethyl)propanoic acid: An intermediate of S-013420

A safe, scalable process was developed for nitric acid oxidation of 3-bromo-2,2-bis(bromomethyl)propan-1-ol (2) to give 3-bromo-2,2-bis(bromomethyl) propanoic acid (3), an intermediate in the synthesis of S-013420 (1). The key points are the use of a catalytic amount of NaNO2 and addition of the starting material in portions. We achieved 3,000 L scale pilot production.