52837-54-4

Basic information

• Product Name: 2,2,5-Trimethyloxazolidine
• Synonyms: 2,2,5-Trimethyloxazolidine
• CAS NO: 52837-54-4
• Molecular Formula: C₆H₁₃NO
• Molecular Weight: 115.1735
• Mol File: 52837-54-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 133.3°Cat760mmHg
• Flash Point: 42.6°C
• Appearance: /
• Density: 0.858g/cm³
• Vapor Pressure: 8.51mmHg at 25°C
• Refractive Index: 1.403
• CAS DataBase Reference: 2,2,5-Trimethyloxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,5-Trimethyloxazolidine(52837-54-4)
• EPA Substance Registry System: 2,2,5-Trimethyloxazolidine(52837-54-4)

Safety Data

• Hazardous Substances Data: 52837-54-4(Hazardous Substances Data)

Usage

Classification

Oxazolidine (a type of cyclic organic compound)

Appearance

Colorless liquid with a mild odor

Solubility

Soluble in water and many organic solvents

Uses

+ Stabilizer and corrosion inhibitor in industrial processes (e.g. metalworking fluids and lubricants)
+ Chemical intermediate in the production of pharmaceuticals, agricultural chemicals, and other specialty chemicals
+ Precursor in the synthesis of polymers and other organic compounds

InChI:InChI=1/C6H13NO/c1-5-4-7-6(2,3)8-5/h5,7H,4H2,1-3H3

Upstream product

• 3156-73-8 2-hydroxy-1-nitropropane 
• 78-96-6 3-amino-2-propanol 
• 67-64-1 acetone 

Downstream Products

• 52836-31-4 R-29148 

Relevant articles and documents

One-pot Synthesis, Crystal structure, and Bioactivity of N-Phenoxyacetyl-2,4,5-trisubstituted-1,3-oxazolidines

N-phenoxyacetyl-1,3-oxazolidine derivatives were synthesized by the cyclization and acylation with β-amino alcohol, ketone, and phenoxyacetyl chloride as the starting materials. All compounds were characterized by IR, 1H NMR, 13C NMR, ESI-MS, and elemental analysis. The configuration of 4a was determined by X-ray crystallography. The preliminary biological tests showed that all products could protect soybean against injury caused by 2,4-D butylate to some extent.

Preparation of 3-dihaloacetyl oxazolidines

The disclosure herein relates to a new process for the preparation of 3-dihaloacetyl (un)substituted oxazolidine compounds by the catalytic hydrogenation of nitroalcohols with aldehydes or ketones followed by reaction with a dihaloacetyl halide.

Synthesis of 2,2-Disubstituted N-Nitrosooxazolidines with Nitrosyl Chloride

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