5285-85-8 Usage
Description
(R,R)-()-2-nitro-1-phenylpropane-1,3-diol is a chiral compound characterized by the presence of a nitro group and a phenyl group attached to a propanediol backbone. (R,R)-()-2-nitro-1-phenylpropane-1,3-diol is known for its unique stereochemistry, which is crucial in various chemical and pharmaceutical applications due to its distinct biological activities.
Uses
Used in Pharmaceutical Synthesis:
(R,R)-()-2-nitro-1-phenylpropane-1,3-diol is utilized as a chiral building block in the synthesis of pharmaceuticals. Its chiral nature allows for the production of enantiomerically pure drugs, which is essential for ensuring the desired therapeutic effects and minimizing potential side effects associated with the less active enantiomer.
Used in Agrochemical Production:
In the agrochemical industry, (R,R)-()-2-nitro-1-phenylpropane-1,3-diol serves as a key intermediate for the development of chiral agrochemicals. (R,R)-()-2-nitro-1-phenylpropane-1,3-diol's stereochemistry plays a vital role in determining the effectiveness and selectivity of these products, contributing to more targeted and environmentally friendly pest control solutions.
Used in Chiral Ligand and Catalyst Preparation:
(R,R)-()-2-nitro-1-phenylpropane-1,3-diol is also employed in the preparation of chiral ligands and catalysts for asymmetric synthesis. These chiral catalysts and ligands are indispensable in the production of optically active compounds, which are often required for biological activity and are crucial in the development of new drugs and other bioactive molecules.
Used as a Versatile Organic Chemistry Intermediate:
The nitro group in (R,R)-()-2-nitro-1-phenylpropane-1,3-diol provides a handle for further chemical modification, making it a versatile intermediate in organic chemistry. This allows for the synthesis of a wide range of compounds with various applications, from pharmaceuticals to specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 5285-85-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,8 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5285-85:
(6*5)+(5*2)+(4*8)+(3*5)+(2*8)+(1*5)=108
108 % 10 = 8
So 5285-85-8 is a valid CAS Registry Number.
5285-85-8Relevant articles and documents
Quantitative Evaluation of the Catalytic Activity of Dendrimers with only One Active Center at the Core: Application to the Nitroaldol (Henry) Reaction
Zubia, Aizpea,Cossio, Fernando P.,Morao, Inaki,Rieumont, Marina,Lopez, Xabier
, p. 5243 - 5252 (2007/10/03)
One reference tertiary amine and three families of structurally related trialkylamines and dendrimers have been synthesized, characterized, and studied by molecular dynamics simulations. The catalytic activity of these amines in the nitroaldol (Henry) reaction between 2-nitroethanol and benzaldehyde has been measured by FT-IR spectroscopy. It is found that, in this kind of molecule with only one catalytic center at the core, the efficiency of the catalytic process decreases with the size and/or the degree of ramification of the dendrimer. According to these results, there is a linear departure from the behavior predicted by the hard sphere collision theory (HSCT) as the size of the dendrimer increases. Therefore, the behavior of structurally related dendrimers can be quantified in terms of their molecular weight and reagent accessible surfaces.
