52851-41-9 Usage
Description
4-Hydroxyquinolin-2(1H)-one, also known as Quinoline-2,4(1H,3H)-dione, is an organic compound with the molecular formula C9H6NO2. It is a derivative of quinoline, featuring a hydroxyl group at the 4th position and a ketone group at the 2nd position. 4-Hydroxyquinolin-2(1H)-one is known for its potential applications in various fields due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
4-Hydroxyquinolin-2(1H)-one is used as a reagent for the synthesis of various pharmaceutical compounds. One of its notable applications is in the production of 2H-pyrans, which are important intermediates in the synthesis of a wide range of biologically active molecules. Additionally, this compound is used in the synthesis of the alkaloid Flindersine, which has potential applications in the treatment of certain diseases.
Used in Chemical Synthesis:
In the field of organic chemistry, 4-Hydroxyquinolin-2(1H)-one serves as a key building block for the synthesis of various quinoline-based compounds. These compounds find applications in different industries, such as pharmaceuticals, agrochemicals, and materials science. The unique structure of 4-Hydroxyquinolin-2(1H)-one allows for further functionalization and modification, making it a versatile starting material for the development of new molecules with desired properties.
Used in Research and Development:
4-Hydroxyquinolin-2(1H)-one is also utilized in research and development for the exploration of new chemical reactions and the discovery of novel compounds with potential applications. Its unique structure and reactivity make it an interesting candidate for studying various chemical transformations and understanding the underlying reaction mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 52851-41-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,8,5 and 1 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 52851-41:
(7*5)+(6*2)+(5*8)+(4*5)+(3*1)+(2*4)+(1*1)=119
119 % 10 = 9
So 52851-41-9 is a valid CAS Registry Number.
52851-41-9Relevant articles and documents
A Cu-Doped ZIF-8 metal organic framework as a heterogeneous solid catalyst for aerobic oxidation of benzylic hydrocarbons
Nagarjun, Nagarathinam,Dhakshinamoorthy, Amarajothi
, p. 18702 - 18712 (2019/12/09)
Mixed-metal metal organic frameworks have received considerable attention in recent years and it has been shown that the activity of the parent metal organic framework (MOF) is often enhanced upon doping with external metal ions within the framework. In this context, Cu2+ ions with different loadings were incorporated within the ZIF-8 framework to obtain a series of Cu-doped ZIF-8 materials and their activity was examined in the aerobic oxidation of hydrocarbons. The as-synthesized Cu-doped solids were characterized by powder X-ray diffraction (XRD), ultraviolet diffuse reflectance spectroscopy (UV-DRS), scanning electron microscopy (SEM), Fourier Transform infrared (FT-IR), electron paramagnetic resonance (EPR) and inductively coupled plasma (ICP) analysis. The experimental results revealed that the activity of Cu-doped ZIF-8 is much higher than that of the parent ZIF-8 in all the tested substrates at 120 °C. Furthermore, the activity of the Cu-doped ZIF-8 with the highest Cu loading was eight fold higher than that of the parent ZIF-8 in the aerobic oxidation of cyclooctane (1) at 120 °C with more than 80% selectivity to the corresponding cyclooctanol/cyclooctanone (ol/one) mixture. Cu-doped ZIF-8 was reused two times with no significant drop in its activity under identical conditions. Furthermore, comparison of the two times reused solid with that of the fresh solid by powder XRD and SEM analysis revealed identical structural integrity and morphology, respectively during the oxidation reactions.