528571-18-8

Basic information

• Product Name: 1-benzyl-3-bromo-4-(5-chloro-pentyl)-3-(toluene-4-sulfonyl)-piperidine-2,6-dione
• Synonyms: 1-benzyl-3-bromo-4-(5-chloro-pentyl)-3-(toluene-4-sulfonyl)-piperidine-2,6-dione
• CAS NO: 528571-18-8
• Molecular Weight: 540.906
• Mol File: 528571-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3-bromo-4-(5-chloro-pentyl)-3-(toluene-4-sulfonyl)-piperidine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-bromo-4-(5-chloro-pentyl)-3-(toluene-4-sulfonyl)-piperidine-2,6-dione(528571-18-8)
• EPA Substance Registry System: 1-benzyl-3-bromo-4-(5-chloro-pentyl)-3-(toluene-4-sulfonyl)-piperidine-2,6-dione(528571-18-8)

Safety Data

• Hazardous Substances Data: 528571-18-8(Hazardous Substances Data)

Upstream product

• 528570-89-0 1-benzyl-3-bromo-3-(4-methylphenylsulfonyl)-4-(5-hydroxypentyl)piperidine-2,6-dione 
• 34067-76-0 6-hydroxyhexanal 
• 2564-06-9 N-benzyl-2-chloroacetamide 
• 100-46-9 benzylamine 
• 181274-00-0 (E)-8-Hydroxy-oct-2-enoic acid ethyl ester 
• 330173-08-5 N-benzyl-2-(4-methylphenylsulfonyl)acetamide 

Relevant articles and documents

1,8-Diazabicyclo[5.4.0]undec-7-ene: A remarkable base in the debromination of 4- or 5-substituted N-benzyl α-bromo-α-p- toluenesulfonylglutarimide

Debromination of N-benzyl 4- or 5-substituted α-bromo-α-p- toluenesulfonylglutarimides is achieved with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) to give the N-benzyl 4- or 5-substituted α-p- toluenesulfonylglutarimides. The DBU/THF system is applied to a new methodology for the synthesis of bicyclic glutarimide skeleton in moderate yields.